Budget Amount *help |
¥25,740,000 (Direct Cost: ¥19,800,000、Indirect Cost: ¥5,940,000)
Fiscal Year 2020: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2019: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2018: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2017: ¥16,510,000 (Direct Cost: ¥12,700,000、Indirect Cost: ¥3,810,000)
|
Outline of Final Research Achievements |
We investigated the interaction of benzyl isothiocyanate (BITC) with biomolecules. BITC modified ethanolamine was detected from cultured cells after treatment of BITC. It was suggested that phosphatidylethanolamine modified with BITC was degraded by phosphatases. In addition, some proteins were modified with BITC. A correlation was found between the activity and BITC modification in one of the modified proteins, suggesting that BITC directly regulated the protein activity via the modification.
|