| Budget Amount *help |
¥15,340,000 (Direct Cost: ¥11,800,000、Indirect Cost: ¥3,540,000)
Fiscal Year 2019: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2018: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2017: ¥10,400,000 (Direct Cost: ¥8,000,000、Indirect Cost: ¥2,400,000)
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| Outline of Final Research Achievements |
I established a technique for imaging living cells inside the body, such as mice, for application to regenerative medicine. I have synthesized fluorescent nano-particle probes that can be observed with the second near‐infrared window of light (wavelengths from 950 nm to 1600 nm) and fabricated a laser-operated microscopy system to observe them. The synthesis of Y2O3:Yb nanoparticles showing 1030 nm fluorescence at 980 nm excitation and Y2O3:Nd nanoparticles showing fluorescence around 1050 to 1100 nm at 820 nm excitation were performed as fluorescent probes. These nanoparticles were observed through 2% intralipid solution and successfully imaged at a depth of 1.5 mm. It was also demonstrated that cellular imaging is possible.
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