| Budget Amount *help |
¥25,350,000 (Direct Cost: ¥19,500,000、Indirect Cost: ¥5,850,000)
Fiscal Year 2020: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2019: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2018: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2017: ¥10,270,000 (Direct Cost: ¥7,900,000、Indirect Cost: ¥2,370,000)
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| Outline of Final Research Achievements |
This study aimed to delineate determinants of ambulatory home-cage activity and examined how changes in home-cage activity affect hippocampal neurogenesis in mice. We found that changes in housing condition (environmental enrichment, small cage) did not affect ambulatory home-cage activity in mice, suggesting that physical activity is regulated in a homeostatic manner, and social interaction might be a critical for the homeostatic regulation of physical activity. We also found that increasing absolute amount of physical activity is not a critical factor for improving brain function, but physical activity with social interaction is more important. Our finding would help for better understanding of regulation of physical activity and preventing physical inactivity, a risk factor for neuropsychological disorders.
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