| Budget Amount *help |
¥24,960,000 (Direct Cost: ¥19,200,000、Indirect Cost: ¥5,760,000)
Fiscal Year 2019: ¥8,060,000 (Direct Cost: ¥6,200,000、Indirect Cost: ¥1,860,000)
Fiscal Year 2018: ¥8,710,000 (Direct Cost: ¥6,700,000、Indirect Cost: ¥2,010,000)
Fiscal Year 2017: ¥8,190,000 (Direct Cost: ¥6,300,000、Indirect Cost: ¥1,890,000)
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| Outline of Final Research Achievements |
A thermal measurement deice with high-temperature resolution for single cultured cells were developed. The device had vanadium oxide thermistors as temperature sensors, suspended membrane structure under the sensors for thermal insulation, and a chamber for cell culturing. The device was fabricated using microfabrication techniques. The temperature signals from the cells cultured on the device were measured. The gradual and long-time temperature increase was observed by chemical stimulating. Also, the signals at the environment temperature of 25 and 37°C were compared, resulting in the larger temperature fluctuation at 37°C. We succeeded in developing the target device and measuring the temperature signals of single cultured cells.
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