Development of novel graphene nanopore sensor for DNA sequencing

• Project/Area Number: 17H04907
• Research Category: Grant-in-Aid for Young Scientists (A)
• Allocation Type: Single-year Grants
• Research Field: Thermal engineering
• Research Institution: Kyushu University
• Principal Investigator: Wang Haidong 九州大学, 工学研究院, 助教 (30729405)
• Project Period (FY): 2017-04-01 – 2019-03-31
• Project Status: Discontinued (Fiscal Year 2018)
• Budget Amount: ¥24,180,000 (Direct Cost: ¥18,600,000、Indirect Cost: ¥5,580,000); Fiscal Year 2018: ¥7,670,000 (Direct Cost: ¥5,900,000、Indirect Cost: ¥1,770,000); Fiscal Year 2017: ¥11,830,000 (Direct Cost: ¥9,100,000、Indirect Cost: ¥2,730,000)
• Keywords: graphene / MEMS sensor / nanopore drilling / DNA molecule / sensor / DNA / nanopore / thermal rectification / nanowire / ナノバイオ / グラフェン / ナノポアセンサ / DNA シークエ ンシング

Outline of Annual Research Achievements

The research was smoothly carried out in the last year. We have made important achievements in the research project as following:
1. We have proposed a new method for drilling sub 10 nm pore in a suspended monolayer graphene for detecting single DNA molecule.
2. We have successfully fabricated a MEMS sensor device with nano-channel. This new liquid testing device is much simpler than the normal micro/nano channel devices and the depth of the nano-channel can be precisely controlled.
A single molecule can be guided along the nano-channel to pass through the nanopore in graphene, realizing DNA sequencing.

Research Progress Status

平成30年度が最終年度であるため、記入しない。

Strategy for Future Research Activity

平成30年度が最終年度であるため、記入しない。

Research Products

• [Journal Article] Experimental study of thermal rectification in suspended monolayer graphene (2017)
  • Author(s): Wang Haidong、Hu Shiqian、Takahashi Koji、Zhang Xing、Takamatsu Hiroshi、Chen Jie
  • Journal Title: Nature Communications Volume: 8 Issue: 1 Pages: 15843-15843
  • DOI: 10.1038/ncomms15843
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Benchmark characterization of the thermoelectric properties of individual single-crystalline CdS nanowires by a H-type sensor (2017)
  • Author(s): Haidong Wang, Dingshan Zheng, Xing Zhang, Hiroshi Takamatsu and Weida Hu
  • Journal Title: RSC Advances Volume: 7 Issue: 41 Pages: 25298-25304
  • DOI: 10.1039/c7ra02734f
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Presentation] 単層グラフェンの熱流束制御技術に関する研究 (2017)
  • Author(s): Haidong Wang
  • Organizer: 第65回応用物理学会春季学術講演会
  • Invited
• [Presentation] Thermal rectification in suspended monolayer graphene (2017)
  • Author(s): Haidong Wang
  • Organizer: USJ2017 workshop
  • Int'l Joint Research
• [Presentation] 架橋単層カーボンナノチュブの熱伝導解析 (2017)
  • Author(s): Haidong Wang
  • Organizer: 第55回 日本伝熱シンポジウム
• [Presentation] Effective thermal rectification in suspended monolayer graphene (2017)
  • Author(s): Haidong Wang
  • Organizer: 16th International Heat Transfer Conference
  • Int'l Joint Research