Budget Amount *help |
¥23,400,000 (Direct Cost: ¥18,000,000、Indirect Cost: ¥5,400,000)
Fiscal Year 2020: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2019: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2018: ¥6,630,000 (Direct Cost: ¥5,100,000、Indirect Cost: ¥1,530,000)
Fiscal Year 2017: ¥7,020,000 (Direct Cost: ¥5,400,000、Indirect Cost: ¥1,620,000)
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Outline of Final Research Achievements |
Two-photon calcium imaging has revealed neuronal activities related to behavioral and cognitive functions in rodents at a single-cell resolution. To apply this technique to behaving non-human primates, we developed protocols to train head-fixed common marmosets to perform upper-limb movement tasks. Head-fixed marmosets could control a pole with an upper limb to move a cursor to a target on a screen. We conducted two-photon calcium imaging of layer 2/3 neurons in the motor cortex during this motor task performance, and detected task-relevant activity from neuronal somata, dendrites and axons.
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