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Research Project

Project/Area Number 17H05014
Research Category

Grant-in-Aid for Young Scientists (A)

Allocation TypeSingle-year Grants
Research Field Evolutionary biology
Research InstitutionKanagawa University (2020-2021)
Okayama University (2017-2019)

Principal Investigator

Takahashi Kazuo  神奈川大学, 理学部, 教授 (10450199)

Project Period (FY) 2017-04-01 – 2021-03-31
Project Status Completed (Fiscal Year 2021)
Budget Amount *help
¥26,000,000 (Direct Cost: ¥20,000,000、Indirect Cost: ¥6,000,000)
Fiscal Year 2020: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2019: ¥7,800,000 (Direct Cost: ¥6,000,000、Indirect Cost: ¥1,800,000)
Fiscal Year 2018: ¥7,150,000 (Direct Cost: ¥5,500,000、Indirect Cost: ¥1,650,000)
Fiscal Year 2017: ¥7,410,000 (Direct Cost: ¥5,700,000、Indirect Cost: ¥1,710,000)
Keywords隠蔽変異 / HSP90 / ゲノムワイド関連解析 / ロバストネス / 干渉色 / 自動活動計測 / 遺伝的ロバストネス / 量的遺伝学
Outline of Final Research Achievements

For organisms, heritability of shape and size is one of the factors that directly affects the rate of evolution. For example, if certain traits such as morphology, body color or behavior is easy to inherit and certain trait value is more advantageous, it is expected that the traits of the organism will evolve quickly in a certain direction. In this research, I aimed to understand the genetic mechanism controlling heritability. As a result, it was confirmed that there are multiple genes on the genome thought to have such functions.

Academic Significance and Societal Importance of the Research Achievements

本研究では、分子シャペロンの一つであるHSP90が様々な形質の「遺伝しやすさ」に影響することをゲノム網羅的なアプローチによって示した。ゲノムの塩基配列とその結果として生じる形質の関係は必ずしも厳密に決定されている訳では無い事、また、HSP90の制御対象がゲノム全域に及んでいる可能性が示唆された。本研究で得られた知見は、生物の進化可能性に関する基礎的な理解を進めるだけでなく、育種における複雑な人為淘汰の効率化にもつながる可能性がある。

Report

(5 results)
  • 2021 Final Research Report ( PDF )
  • 2020 Annual Research Report
  • 2019 Annual Research Report
  • 2018 Annual Research Report
  • 2017 Annual Research Report
  • Research Products

    (8 results)

All 2020 2019 2018 2017

All Journal Article (4 results) (of which Peer Reviewed: 4 results) Presentation (4 results)

  • [Journal Article] Apoptosis inhibition mitigates aging effects in Drosophila melanogaster2020

    • Author(s)
      Hiroaki Kidera, Toshimitsu Hatabu and Kazuo H. Takahashi
    • Journal Title

      Genetica

      Volume: 148 Issue: 2 Pages: 69-76

    • DOI

      10.1007/s10709-020-00088-1

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] HSP90 as a global genetic modifier for male genital morphology in Drosophila melanogaster2018

    • Author(s)
      Kazuo H. Takahashi Motoyuki Ishimori Hiroyoshi Iwata
    • Journal Title

      Evolution

      Volume: 72 Issue: 11 Pages: 2419-2434

    • DOI

      10.1111/evo.13598

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Multiple modes of canalization: Links between genetic, environmental canalizations and developmental stability, and their trait-specificity2018

    • Author(s)
      Kazuo H. Takahashi
    • Journal Title

      Seminars in Cell & Developmental Biology

      Volume: 88 Pages: 14-20

    • DOI

      10.1016/j.semcdb.2018.05.018

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Geometric morphometrics in entomology: Basics and applications2017

    • Author(s)
      Tatsuta Haruki、Takahashi Kazuo H.、Sakamaki Yositaka
    • Journal Title

      Entomological Science

      Volume: 21 Issue: 2 Pages: 164-184

    • DOI

      10.1111/ens.12293

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Presentation] ハイパースペクトル画像解析による昆虫の翅干渉色の定量化2019

    • Author(s)
      高橋一男
    • Organizer
      日本生態学会第66回全国大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 雑種の翅は何色か?:ショウジョウバエの翅干渉色の遺伝形式2019

    • Author(s)
      高橋一男
    • Organizer
      第63回日本応用動物昆虫学会大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] ハイパースペクトル画像解析による昆虫の翅干渉色の定量化法の検討2018

    • Author(s)
      高橋一男
    • Organizer
      西日本応用動物昆虫研究会例会
    • Related Report
      2018 Annual Research Report
  • [Presentation] ハイパースペクトル画像解析による昆虫の翅干渉色の定量化法の検討2017

    • Author(s)
      高橋一男
    • Organizer
      日本応用動物昆虫学会
    • Related Report
      2017 Annual Research Report

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Published: 2017-04-28   Modified: 2023-01-30  

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