| Budget Amount *help |
¥24,440,000 (Direct Cost: ¥18,800,000、Indirect Cost: ¥5,640,000)
Fiscal Year 2019: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2018: ¥7,800,000 (Direct Cost: ¥6,000,000、Indirect Cost: ¥1,800,000)
Fiscal Year 2017: ¥11,180,000 (Direct Cost: ¥8,600,000、Indirect Cost: ¥2,580,000)
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| Outline of Final Research Achievements |
In mammal, Germ cells undergo meiosis to differentiate into sperm and eggs. Although germ cells increase in number by mitosis prior to meiosis, it is still unclear how they switch from mitosis to meiosis. We have previously succeeded in inducing meiotic-like cells by repressing the Max gene in ES cells. The main objective of this project was to prove that the in vivo phenomena observed in ES cells can also be observed in vivo.
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