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Realization of slow breathing exercise to increase parasympathetic nervous activity in chronic diseases patients

Research Project

Project/Area Number 17H05107
Research Category

Grant-in-Aid for Young Scientists (A)

Allocation TypeSingle-year Grants
Research Field Fundamental nursing
Research InstitutionMiyagi University (2020-2021)
Ibaraki Christian University (2017-2019)

Principal Investigator

Kaneko Kentaro  宮城大学, 看護学群, 講師 (40714358)

Project Period (FY) 2017-04-01 – 2021-03-31
Project Status Completed (Fiscal Year 2021)
Budget Amount *help
¥11,310,000 (Direct Cost: ¥8,700,000、Indirect Cost: ¥2,610,000)
Fiscal Year 2020: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2019: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2018: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2017: ¥5,720,000 (Direct Cost: ¥4,400,000、Indirect Cost: ¥1,320,000)
Keywords副交感神経活動リザーブ / Slow breathing exercise / 慢性疾患患者 / 動物実験 / 環境エンリッチメント / Slow Breathing Exercise / 看護介入 / 慢性疾患
Outline of Final Research Achievements

The aim of this study was to investigate the clinical effects of slow breathing exercise (SBE) in chronic disease patients, focusing on autonomic nervous activity, especially parasympathetic activity at rest. The results showed that parasympathetic nervous activity was lower in patients with chronic kidney disease than in healthy subjects. In addition, the results suggest that continuous SBE intervention may increase parasympathetic nervous activity and affect cardio dynamics, and that although SBE is a relatively simple method of incorporating deep breathing into daily life, its effectiveness may be related to the rate at which it is practiced. Furthermore, in animal experiments using disease models, continuous intervention with environmental enrichment to increase parasympathetic nerve activity was found to maintain a high level of parasympathetic nerve activity even as the disease progressed. Further study is required on subject-specific SBE methods and other physiological effects.

Academic Significance and Societal Importance of the Research Achievements

自律神経活動指標を用いた看護援助技術の検証は多くあるが、安静時の副交感神経活動に着目し、かつそれを高めるための看護介入という観点から行われた研究は少ない。本研究によってSBEは有疾患患者においても副交感神経活動リザーブを高める効果を有しており、かつ、特別な道具を用いることなく、いつでも取り組むことができる安全な看護介入であることを示した。副交感神経活動リザーブを高める看護介入を早期から導入することで、発症予防や重症化抑制への寄与といった応用が期待される。

Report

(5 results)
  • 2021 Final Research Report ( PDF )
  • 2020 Annual Research Report
  • 2019 Annual Research Report
  • 2018 Annual Research Report
  • 2017 Annual Research Report
  • Research Products

    (6 results)

All 2021 2020 2019 2018 2017

All Journal Article (2 results) (of which Int'l Joint Research: 2 results,  Peer Reviewed: 2 results,  Open Access: 2 results) Presentation (4 results) (of which Int'l Joint Research: 3 results)

  • [Journal Article] Effects of slow breathing exercise in chronic kidney disease patients2021

    • Author(s)
      Kaneko Kentaro, Taneichi Akira, Sato Yuko, Kawaguchi Hiroshi, Yamamoto Machiko
    • Journal Title

      International Medical Journal

      Volume: 28 Pages: 681-683

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Effects of environmental enrichment on autonomic nervous activity in NSY mice2020

    • Author(s)
      Kentaro Kaneko, Akitoshi Chikamoto, Julia Chu-Ning Hsu, Ryota Tochinai, Shin-ichi Sekizawa, Machiko Yamamoto, Masayoshi Kuwahara
    • Journal Title

      Experimental Animals

      Volume: 69 Issue: 2 Pages: 161-167

    • DOI

      10.1538/expanim.19-0103

    • NAID

      130007835091

    • ISSN
      0007-5124, 1341-1357, 1881-7122
    • Related Report
      2020 Annual Research Report 2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Presentation] Can slow breathing exercise improve the autonomic nervous imbalance in chronic kidney disease patients?2019

    • Author(s)
      Kentaro Kaneko, Shin-ichi Sekizawa, Ryota Tochinai, Machiko Yamamoto, Masayoshi Kuwahara
    • Organizer
      International Congress on Electrocardiology 2019, Joint meeting of ISHNE and ISE
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Can slow breathing exercise improve the autonomic nervous imbalance in chronic kidney disease patients ?2019

    • Author(s)
      Kentaro Kaneko, Shin-ichi Sekizawa, Ryota Tochinai, Machiko Yamamoto, Masayoshi Kuwahara
    • Organizer
      International Congress on Electrocardiology 2019, Joint meeting of ISHNE and ISE
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 糖尿病モデルマウスにおける病態と自律神経系機能に及ぼす環境エンリッチメントの影響2018

    • Author(s)
      金子健太郎、近本明俊、関澤信一、山本真千子、桑原正貴
    • Organizer
      第65回日本実験動物学会総会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Evaluation of autonomic nervous functions in chronic kidney disease patients by tone-entropy analysis2017

    • Author(s)
      Kentaro Kaneko, Machiko Yamamoto, Masayoshi Kuwahara
    • Organizer
      The 44th International Congress on Electrocardiology
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research

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Published: 2017-04-28   Modified: 2023-01-30  

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