| Budget Amount *help |
¥26,000,000 (Direct Cost: ¥20,000,000、Indirect Cost: ¥6,000,000)
Fiscal Year 2019: ¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000)
Fiscal Year 2018: ¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000)
Fiscal Year 2017: ¥13,260,000 (Direct Cost: ¥10,200,000、Indirect Cost: ¥3,060,000)
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| Outline of Final Research Achievements |
In this study, we have developed practical asymmetric synthetic methods for chiral silicon molecules having asymmetric silicon atom to open up new chiral technology based on their unique properties. As the results, we have achieved asymmetric synthesis of chiral silacycles, e.g. chiral silacyclopentanes, chiral silaoxane with newly developed asymmetric reactions, and found that some of the derivatives show substantial bioactivity.
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