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Functional role of the frontal lobe with "brain timer"

Research Project

Project/Area Number 17K00216
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Cognitive science
Research InstitutionKindai University

Principal Investigator

OSHIO Ken-ichi  近畿大学, 医学部, 講師 (30296751)

Project Period (FY) 2017-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2019: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2018: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywords時間知覚 / 大脳生理学 / 電気生理学 / 前頭葉 / 認知科学
Outline of Final Research Achievements

We can stop a stopwatch in ten seconds with eyes closed. This suggests that our brain have timing function such as a “stopwatch”. Nonetheless, it is unclear how physical time is transformed into brain time. Temporal interval is a modality-independent physical attribute which can be perceived whether it is assigned to a visual, auditory or somatic stimulus. The frontal lobe receives inputs from multiple sensory systems and plays a role in integrating sensory information. It is therefore natural to speculate that the frontal lobe would participate in time perception and represent temporal attributes in some way. Monkeys were trained to discriminate between temporal durations associated with visual or auditory stimuli. Neuronal activity was recorded while the subjects were performing the task. We found various types neurons exhibiting phasic activity and sustained activity, and so on, which were associated with temporal processing from the prefrontal cortex and the premotor cortex.

Academic Significance and Societal Importance of the Research Achievements

時間は身の回りに溢れる基本的な物理量であるにもかかわらず、脳が具体的にどうやって時間の長さを計っているのかということは未だほとんど分かっていない。うつ病、ADHD、統合失調症といった患者に時間感覚の歪みが見られることも分かってきており、脳内ストップウォッチの解明は、脳の機能を理解するにとどまらず、精神疾患の理解や、精神状態や気分の客観的指標への応用にもつながると期待される。

Report

(4 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Research-status Report
  • 2017 Research-status Report
  • Research Products

    (9 results)

All 2020 2019 2018 2017

All Journal Article (3 results) (of which Peer Reviewed: 2 results) Presentation (6 results) (of which Int'l Joint Research: 1 results)

  • [Journal Article] Neuronal activity of the monkey prefrontal cortex in a duration estimation and production task2020

    • Author(s)
      Chiba A, Morita K, Oshio K, Inase M
    • Journal Title

      J Physiol Sci

      Volume: 70(1)

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Interval timing of visual and auditory cues for duration discrimination in monkey prefrontal cortex2019

    • Author(s)
      Chiba A, Morita K, Oshio K, Inase M
    • Journal Title

      J Physiol Sci

      Volume: 69(1)

    • Related Report
      2018 Research-status Report
    • Peer Reviewed
  • [Journal Article] Neuronal activity involved in temporal classification in the monkey medial premotor areas2018

    • Author(s)
      Chiba A, Oshio K, Inase M
    • Journal Title

      J Physiol Sci

      Volume: 68(Suppl. 1)

    • Related Report
      2017 Research-status Report
  • [Presentation] 時間知覚・生成課題におけるサル前頭前野の神経細胞活動2020

    • Author(s)
      千葉惇、守田和紀、生塩研一、稲瀬正彦
    • Organizer
      第97回日本生理学会大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 異種感覚刺激の時間弁別におけるサル内側運動前野での時間情報表現2019

    • Author(s)
      千葉惇、守田和紀、生塩研一、稲瀬正彦
    • Organizer
      第42回日本神経科学大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Interval timing of visual and auditory cues for duration discrimination in monkey prefrontal cortex2019

    • Author(s)
      Chiba A, Morita K, Oshio K, Inase M
    • Organizer
      第96回日本生理学会大会, Federation of the Asia and Oceanian Physiological Societies 9th meeting (FAOPS2019)
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research
  • [Presentation] サル背内側前頭皮質の神経細胞における時間認知機構2018

    • Author(s)
      千葉惇, 生塩研一, 稲瀬正彦
    • Organizer
      第41回日本神経科学大会
    • Related Report
      2018 Research-status Report
  • [Presentation] サル前頭前野と内側運動前野で共有される時間計測関連活動2018

    • Author(s)
      千葉惇、生塩研一、稲瀬正彦
    • Organizer
      第94回日本生理学会大会
    • Related Report
      2017 Research-status Report
  • [Presentation] サル前頭前野と内側運動前野における特徴的な時間計測関連活動2017

    • Author(s)
      千葉惇、生塩研一、稲瀬正彦
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Research-status Report

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Published: 2017-04-28   Modified: 2021-02-19  

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