Evaluation of long-term nutritional status of geriatric patients using scalp hair components.
Project/Area Number |
17K00870
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Eating habits
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Research Institution | Health Sciences University of Hokkaido |
Principal Investigator |
KIMURA Osamu 北海道医療大学, 薬学部, 講師 (10418882)
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Project Period (FY) |
2017-04-01 – 2020-03-31
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Project Status |
Completed (Fiscal Year 2019)
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Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2019: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2018: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2017: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
|
Keywords | 頭髪 / 炭素安定同位体 / 窒素安定同位体 / 経腸栄養 / 中心静脈栄養 / 高齢者 / 微量元素 / 安定同位体比 / 栄養 / 栄養学 / 安定同位体 |
Outline of Final Research Achievements |
The stable isotope ratios (δ13C and δ15N) and trace elements in the scalp hair of patients who received enteral or parenteral nutrition were analyzed to assess long-term nutritional status of geriatric patients. The values of δ13C and δ15N in the scalp hair of geriatric patients ingesting enteral nutrition for long period may be good indicators to estimate nutritional status of patients. The duration of parenteral nutrition can be estimated by the δ13C and δ15N levels in the scalp hair of geriatric patients who are nutritionally controlled by parenteral nutrition. Deficiency and excess of trace elements could be estimated by the concentration of trace elements in the patient’s scalp hair.
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Academic Significance and Societal Importance of the Research Achievements |
臨床検査の多くは血液を用いているが、得られるデータのほとんどは採血時のものである。一方、頭髪は1ヶ月に約1cmずつ伸長するので、頭髪からは経時的かつ長期間の情報を得ることが可能である。頭髪は、経腸栄養や中心静脈栄養により長期間栄養管理を受けている患者、また糖尿病、高血圧、腎疾患などの慢性疾患をもつ患者の栄養評価に適した生体試料である。本研究では、高齢者の頭髪に含まれる炭素と窒素の安定同位体比および微量元素を測定することにより、高齢者の長期栄養状態の評価を試みた。
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Report
(4 results)
Research Products
(9 results)
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[Journal Article] Nutritional assessment using stable isotope ratios of carbon and nitrogen in the scalp hair of geriatric patients who received enteral and parenteral nutrition formulas2017
Author(s)
Hayasaka, M., Ogasawara, H., Hotta, Y., Tsukagoshi, K., Kimura, O., Kura, T., Tarumi, T., Muramatsu, H., and Endo, T.
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Journal Title
Clin. Nutr.
Volume: 36
Issue: 6
Pages: 1661-1668
DOI
Related Report
Peer Reviewed
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[Journal Article] Correlation between mercury concentration, and stable isotope ratios of carbon and nitrogen of amino acids in scalp hair from whale meat eaters and heavy fisheaters.2017
Author(s)
Endo, T., Hayasaka, M., Ogasawara, H., Hotta, Y., Kimura, O., Petzke, K,J.
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Journal Title
Rapid Commun. Mass Spectrom
Volume: 31
Issue: 9
Pages: 745-752
DOI
Related Report
Peer Reviewed / Int'l Joint Research
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