| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2019: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2018: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
|
|---|
| Outline of Final Research Achievements |
Our research aims to establish a unified standard of measuring anti-obesity activity by refining a cultured cell evaluation system into a system that can predict elimination of obesity at the individual level.
In this research project, we are screening for lipophilic ingredients that may have anti-obesity effects from Krill oil, which has long been used as an oil to protect the health of people who consume a meat-centered diet with few vegetables, such as those living in Antarctica. We have successfully discovered several functional ingredients. The components from krill oil that promote adipogenesis of 3T3-L1 cells were screened to reveal palmitoyl lactic acid (PLA) as a promoter of adipogenesis. The PLA-induced adipocytes contained large number of small lipid droplets.
|
