| Project/Area Number |
17K01426
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Medical systems
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| Research Institution | Kanagawa Institute of Technology |
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Principal Investigator |
TAKEO HIDEYA 神奈川工科大学, 工学部, 教授 (90434414)
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| Project Period (FY) |
2017-04-01 – 2020-03-31
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| Project Status |
Completed (Fiscal Year 2019)
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| Budget Amount *help |
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2019: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2018: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2017: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
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| Keywords | 網膜症 / 眼底画像 / 経時差分画像 / コンピュータ支援画像診断 / 臨床評価 / 糖尿病網膜症 / 差分画像 / 画像工学 / 黄斑部 / 点状出血 / 医用画像処理 / 認知工学 / 画像認識 |
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| Outline of Final Research Achievements |
We have developed a method of quantitatively expressing the degree of retinopathy symptoms by comparing two eye fundus images, one from the initial diagnosis and the other from follow-up. After conducting high-precision registration of the two images a differential image of the two registered images was created. Next, by calculating the sum of the square of the differential value from the differential image, a quantitative value was obtained that indicates symptomatic changes. In addition, focusing on the changes in the number of petechial hemorrhages that develop in the vicinity of the macula lutea, we weighted changes in numbers of petechial hemorrhages with the quantitative values derived from the differential values mentioned above.
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| Academic Significance and Societal Importance of the Research Achievements |
本研究の独自性・創造性は，眼底画像を用いた糖尿病網膜症の主観的な診断において，経時差分画像と画像解析に基づく黄斑部周辺に生じた点状出血を考慮した定量値により診断に客観性を持たせていることであり，このようなアイデアによる研究は過去に例がなく独創的であると考える．
また，医師の主観や経験年数などの影響も軽減され，正診率が高まることは患者にとって非常に有益なことであることから，本研究の社会的意義は高いと考えられる．
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