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The navigation system for evaluation of motor function in the elderly based on the evaluations of predictive control and feedback control

Research Project

Project/Area Number 17K01496
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Rehabilitation science/Welfare engineering
Research InstitutionKomatsu University (2018-2020)
Tokyo Metropolitan Institute of Medical Science (2017)

Principal Investigator

Lee Jongho  公立小松大学, 保健医療学部, 教授 (40425682)

Project Period (FY) 2017-04-01 – 2021-03-31
Project Status Completed (Fiscal Year 2020)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2019: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2018: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2017: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords老年学 / 予測制御とフィードバック制御
Outline of Final Research Achievements

We developed the navigation system for evaluation of motor function in the elderly based on the evaluation of outputs from predictive and feedback (FB) controllers. By using this system, we evaluated the change in motor function with aging from young subjects in their 20s to elderly subjects in their 70s. In particular, We found that the predictive control deteriorated from the middle-aged subjects, and that the component of microsteps, which is a symptom of Parkinson’s disease, increased significantly at the elderly subjects. Overall, we found that our proposed system allows us to quantitatively analyze not only the decline in predictive control of the cerebellum but also the functional decline of the basal ganglia with aging.

Academic Significance and Societal Importance of the Research Achievements

我々の研究は、人間の運動制御メカニズムに対して「人間の運動は予測制御とフィードバック制御によって行われるし、加齢と共にこの2つの運動制御器の精度や割合が変わって行く」ことを実験的に検証したことに学術的な意義がある。また、我々の研究から構築したデータベースに基づいて高齢者に対する運動機能障害の早期発見や神経疾患の予備群を特定できるシステムとして社会に貢献できると考えられる。

Report

(5 results)
  • 2020 Annual Research Report   Final Research Report ( PDF )
  • 2019 Research-status Report
  • 2018 Research-status Report
  • 2017 Research-status Report
  • Research Products

    (36 results)

All 2021 2020 2019 2018 2017 Other

All Int'l Joint Research (3 results) Journal Article (17 results) (of which Int'l Joint Research: 10 results,  Peer Reviewed: 15 results,  Open Access: 11 results) Presentation (13 results) (of which Int'l Joint Research: 5 results,  Invited: 4 results) Book (1 results) Remarks (1 results) Patent(Industrial Property Rights) (1 results)

  • [Int'l Joint Research] Handong Global University(韓国)

    • Related Report
      2020 Annual Research Report
  • [Int'l Joint Research] Handong Global University(韓国)

    • Related Report
      2019 Research-status Report
  • [Int'l Joint Research] Handong University/Korea University Graduate School/Chosun University(韓国)

    • Related Report
      2017 Research-status Report
  • [Journal Article] The Cerebro-Cerebellum as a Locus of Forward Model: A Review2020

    • Author(s)
      Tanaka Hirokazu、Ishikawa Takahiro、Lee Jongho、Kakei Shinji
    • Journal Title

      Frontiers in Systems Neuroscience

      Volume: 14 Pages: 511301-511301

    • DOI

      10.3389/fnsys.2020.00019

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Dynamic Modulation of a Learned Motor Skill for Its Recruitment2020

    • Author(s)
      Min Kyuengbo、Lee Jongho、Kakei Shinji
    • Journal Title

      Frontiers in Computational Neuroscience

      Volume: 14 Pages: 457682-457682

    • DOI

      10.3389/fncom.2020.457682

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Analysis of Three-Dimensional Circular Tracking Movements Based on Temporo-Spatial Parameters in Polar Coordinates2020

    • Author(s)
      Woong Choi#, Jongho Lee#, Liang Li(#: Co-corresponding authors)
    • Journal Title

      applied sciences

      Volume: 10(2) Issue: 2 Pages: 621-621

    • DOI

      10.3390/app10020621

    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Contribution of the Cerebellum to Predictive Motor Control and Its Evaluation in Ataxic Patients2019

    • Author(s)
      1.Shinji Kakei, Jongho Lee, Hiroshi Mitoma, Hirokazu Tanaka, Mario U Manto, Christiane Susanne Hampe
    • Journal Title

      Frontiers in Human Neuroscience

      Volume: 13 Pages: 216-216

    • DOI

      10.3389/fnhum.2019.00216

    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Muscle synergy analysis for stroke during two degrees of freedom reaching task on horizontal plane2019

    • Author(s)
      Hyeonseok Kim, Jongho Lee, Jaehyo Kim
    • Journal Title

      International Journal of Precision Engineering and Manufacturing

      Volume: 2019 Issue: 2 Pages: 1-10

    • DOI

      10.1007/s12541-019-00251-5

    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Characteristic of motor control in three-dimensional circular tracking movements during monocular vision2019

    • Author(s)
      Woong Choi, Liang Li, Jongho Lee
    • Journal Title

      BioMed Research International

      Volume: 2019 Pages: 3867138-3867138

    • DOI

      10.1155/2019/3867138

    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Consensus Paper. Cerebellar Reserve: From Cerebellar Physiology to Cerebellar Disorders2019

    • Author(s)
      Mitoma H, Buffo A, Gelfo F, Guell X, Fucà E, Kakei S, Lee J, Manto M, Petrosini L, Shaikh AG, Schmahmann JD
    • Journal Title

      Cerebellum

      Volume: 19(1) Issue: 1 Pages: 131-153

    • DOI

      10.1007/s12311-019-01091-9

    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] 腕運動の小脳制御―予測的制御への小脳の関与2019

    • Author(s)
      筧 慎治, 李 鍾昊, 石川享宏, 田中宏和
    • Journal Title

      Clinical Neuroscience

      Volume: 37(8) Pages: 965-968

    • Related Report
      2019 Research-status Report
  • [Journal Article] Physiological and morphological principles underpinning recruitment of the cerebellar reserve2018

    • Author(s)
      Kakei S, Ishikawa T, Lee J, Honda T, Hoffman DS.
    • Journal Title

      CNS Neurol Disord Drug Targets

      Volume: 17 Issue: 3 Pages: 184-192

    • DOI

      10.2174/1871527317666180315164429

    • Related Report
      2018 Research-status Report 2017 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Electromyogram refinement using muscle synergy based regulation of uncertain information2018

    • Author(s)
      Min K, Shin D, Lee J, Kakei S.
    • Journal Title

      J. biomechanics

      Volume: 72 Pages: 125-133

    • DOI

      10.1016/j.jbiomech.2018.03.020

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Electromyography-signal-based muscle fatigue assessment for knee rehabilitation monitoring systems2018

    • Author(s)
      Jongho Lee¶, Hyeonseok Kim¶ and Jaehyo Kim(¶:equally contributed co-first)
    • Journal Title

      Biomedical Engineering Letters

      Volume: 8(4) Issue: 4 Pages: 345-353

    • DOI

      10.1007/s13534-018-0078-z

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Development of a quantitative evaluation system for visuo-motor control in three-dimensional virtual reality space2018

    • Author(s)
      Jongho Lee¶, Woong Choi¶, Naoki Yanagihara, Liang Li, and Jaehyo Kim(¶:equally contributed co-first)
    • Journal Title

      Scientific Reports

      Volume: 8(1) Issue: 1 Pages: 13439-13439

    • DOI

      10.1038/s41598-018-31758-y

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Motor control characteristics for circular tracking movements of human wrist2017

    • Author(s)
      Lee J¶, Kim J¶, Kakei S and Kim J.(¶:equally contributed co-first)
    • Journal Title

      Advanced Robotics

      Volume: 31 Issue: 1-2 Pages: 29-39

    • DOI

      10.1080/01691864.2016.1266121

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Establishment of a quantitative evaluation of wrist motor function recovery stages in stroke patients: Comparison with the Brunnstrom stages2017

    • Author(s)
      Yuji Matsumoto, Jongho Lee, Takatoshi Baba, Shinji Kakei, Yasuhiro Okada, Hiroshi Ando
    • Journal Title

      Bulletin Of Health Sciences Kobe

      Volume: 32 Pages: 45-54

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Diverse coordinate frames on sensorimotor areas in visuomotor transformation2017

    • Author(s)
      Fujiwara Y, Lee J, Ishikawa T, Kakei S, Izawa J
    • Journal Title

      Sci Rep.

      Volume: 7(1) Issue: 1 Pages: 14950-14950

    • DOI

      10.1038/s41598-017-14579-3

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Quantitative Evaluation of Age-related Decline in Control of Preprogramed Movement2017

    • Author(s)
      Shimoda N, Lee J, Kodama M, Kakei S, Masakado Y
    • Journal Title

      PLoS One

      Volume: 12(11) Issue: 11 Pages: e0188657-e0188657

    • DOI

      10.1371/journal.pone.0188657

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 小脳の誤差補正2017

    • Author(s)
      筧 慎治, 石川享宏, 李 鍾昊, 三苫博
    • Journal Title

      Clinical Neuroscience

      Volume: 35(1) Pages: 55-59

    • Related Report
      2017 Research-status Report
  • [Presentation] Development of a novel system to make quantitative evaluation of motor function and clinical applications2021

    • Author(s)
      Jongho Lee
    • Organizer
      2021 1st International Conference of the Brain Korea21 FOUR Interdisciplinary Program in IT-Bio Convergence System
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Quantitative Evaluation of Movement Disorder of the Wrist of Hemiplegic Patients with Cerebral Stroke during the Course of Rehabilitation2019

    • Author(s)
      Yasuhiro Okada, Kenta Fujie, Shiho Suzuki, Tatsuji Morimoto, Kazuya Yoshida, Yuji Matsumoto, Yukihiro Okada, Jongho Lee, Shinji Kakei
    • Organizer
      ISPRM 2019
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] Role of Depth Information for Visuo-Motor Control in Three-Dimensional Virtual Reality Space2019

    • Author(s)
      Jongho Lee, Woong Choi
    • Organizer
      2019 The International Conference on Emotion and Sensibility (ICES 2019)
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] 手首運動を利用した定量的運動機能評価システムの構築と臨床応用:高齢者に対するヘルスケアと医療支援ナビゲーターシステムへの活用2019

    • Author(s)
      Lee J
    • Organizer
      専門家招待セミナー
    • Related Report
      2018 Research-status Report
    • Invited
  • [Presentation] 筋活動と動きの同時計測による運動関連疾患の診断に関する研究2019

    • Author(s)
      李 鍾昊
    • Organizer
      平成30年度生体医歯工学共同研究拠点成果報告会
    • Related Report
      2018 Research-status Report
  • [Presentation] 脳神経疾患の運動機能検査:上肢運動に対する定量化システムと評価方法2018

    • Author(s)
      Lee J
    • Organizer
      平成30年度日本神経学会関東・甲信越地区生涯教育講演会
    • Related Report
      2018 Research-status Report
    • Invited
  • [Presentation] 脳の運動制御能力の分析による高齢者のヘルスケアと医療支援~現状報告と在宅医療への今後の展開~2018

    • Author(s)
      李 鍾昊
    • Organizer
      第1回公立小松大学シーズ・ニーズマッチングシンポジウム
    • Related Report
      2018 Research-status Report
  • [Presentation] 脳神経疾患および脳卒中治療ナビゲーターシステムの構築について2017

    • Author(s)
      Lee J.
    • Organizer
      群馬高専平成29年度電子情報工学科講演会
    • Related Report
      2017 Research-status Report
    • Invited
  • [Presentation] 定量的運動機能評価システムによる早産児の運動発達検査2017

    • Author(s)
      岡崎薫,近藤昌敏,李 鍾昊,筧 慎治
    • Organizer
      第2回TMEDフォーラム
    • Related Report
      2017 Research-status Report
  • [Presentation] Quantitative Evaluation of Smooth Pursuit Arm Movements on Kinect v2 Sensor2017

    • Author(s)
      Takeru Honda, Hirotaka Yoshida, Jongho Lee, Toshiyuki Kondo, Shinji Kakei
    • Organizer
      Neuro2017(the 40st Annual Meeting of the Japan Neuroscience Society)
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Age effects on smooth pursuit arm movement2017

    • Author(s)
      Yoshida H, Honda T, Yozu A, Lee J, Kakei S, Kondo T
    • Organizer
      Neuroscience 2017 (the Society’s 47th annual meeting)
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Development and Ageing Effects on Smooth Pursuit Arm Movement2017

    • Author(s)
      Yoshida H, Honda T, Miyata S, Kumada S, Manabe M, Yozu A, Lee J, Kakei S, Kondo T
    • Organizer
      5th Advances in Neuroinformatics (AINI) 2017
    • Related Report
      2017 Research-status Report
  • [Presentation] Quantitative Evaluation of Motor Control in Smooth Pursuit Arm Movement on Kinect v2 Sensor2017

    • Author(s)
      Takeru Honda, Hirotaka Yoshida, Jongho Lee, Shinji Kakei
    • Organizer
      5th Advances in Neuroinformatics (AINI) 2017
    • Related Report
      2017 Research-status Report
  • [Book] 神経運動失調のみかた、考えかた-小脳と脊髄小脳変性症-「Ⅱ-12. 文字のトラッキング」2017

    • Author(s)
      筧 慎治, 李 鍾昊, 鏡原康裕, 本多武尊, 吉田大峰, 近藤敏之, 三苫 博
    • Total Pages
      358
    • Publisher
      中外医学社
    • ISBN
      4498228901
    • Related Report
      2017 Research-status Report
  • [Remarks] 公益財団法人東京都医学総合研究所 運動障害プロジェクト

    • URL

      http://www.igakuken.or.jp/motor-control/achievement.html

    • Related Report
      2017 Research-status Report
  • [Patent(Industrial Property Rights)] 運動機能解析システム及びそのシステムの作動方法2018

    • Inventor(s)
      筧 慎治,李 鍾昊,織茂智之,稲葉 彰,岡田安弘
    • Industrial Property Rights Holder
      公益財団法人東京都医学総合研究所
    • Industrial Property Rights Type
      特許
    • Filing Date
      2018
    • Acquisition Date
      2018
    • Related Report
      2018 Research-status Report

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Published: 2017-04-28   Modified: 2022-01-27  

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