Longitudinal longitudinal study on elucidation of physical activity pattern for prevention of accreditation for long-term care system in CKD

• Project/Area Number: 17K01610
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Rehabilitation science/Welfare engineering
• Research Institution: Nagoya City University (2019); National Center for Geriatrics and Gerontology (2017-2018)
• Principal Investigator: Lee Sungchul 名古屋市立大学, 大学院システム自然科学研究科, 研究員 (80583666)
• Project Period (FY): 2017-04-01 – 2020-03-31
• Project Status: Completed (Fiscal Year 2019)
• Budget Amount: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000); Fiscal Year 2019: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2018: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2017: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
• Keywords: 腎機能 / 身体活動 / 高齢者 / 座位時間 / CKD / 内臓脂肪 / 身体活動量 / 要介護認定 / eGFR

Outline of Final Research Achievements

In this study, we analyzed the relationship between physical activity and renal function. As a result, it became clear that the longer the sitting time, the more likely it is that renal function will decline. In other words, maintaining physical activity in daily life seems to be important for the prevention of kidney disease. Furthermore, it can be said that maintaining a certain amount of albumin may lead to prevention and improvement of renal function decline.

Academic Significance and Societal Importance of the Research Achievements

本研究では、身体活動と腎機能の低下との関連について明らかにしたものである。４年間の縦断研究の結果であるため因果関係まで説明できると思われる。また、腎機能の予防策として非薬物的方法に着目したことは学術・社会的に意義のある研究であろう。高齢者の割合が世界一である日本において腎臓病の患者さんは増えつつあるが今回の研究成果は予防策の一つとして考えるべきであると思われる。

Research Products

• [Journal Article] Impact of Sedentary Time on Chronic Kidney Disease and Disability Incidence in Community-Dwelling Japanese Older Adults: A 4-Year Prospective Cohort Study (2019)
  • Author(s): Sungchul Lee, Sangyoon Lee, Seongryu Bae, Kazuhiro Harada, Songee Jung, Keitaro Makino, Hiroyuki Shimada
  • Journal Title: J Aging Phys Act . Volume: 27 Issue: 2 Pages: 184-190
  • DOI: 10.1123/japa.2017-0326
  • Peer Reviewed
• [Journal Article] Impact of Sedentary Time on Chronic Kidney Disease and Disability Incidence in Community-Dwelling Japanese Older Adults: A 4-Year Prospective Cohort Study. (2019)
  • Author(s): Lee S, Lee S, Bae S, Harada K, Jung S, Makino K, Shimada H.
  • Journal Title: J Aging Phys Act Volume: 27 Pages: 184-190
  • Peer Reviewed
• [Journal Article] Relationship between chronic kidney disease without diabetes mellitus and components of frailty in community-dwelling Japanese older adults (2017)
  • Author(s): Lee S, Lee S, Bae S, Harada K, Jung S, Imaoka M, Makizako H, Doi T, Shimada H
  • Journal Title: Geriatr Gerontol Int Volume: 18 Issue: 2 Pages: 286-292
  • DOI: 10.1111/ggi.13180
  • Peer Reviewed
• [Journal Article] Relationship between chronic kidney disease with diabetes or hypertension and frailty in community-dwelling Japanese older adults. (2017)
  • Author(s): Lee S, Lee S, Harada K, Bae S, Makizako H, Doi T, Tsutsumimoto K, Hotta R, Nakakubo S, Park H, Suzuki T, Shimada H
  • Journal Title: Geriatrics & Gerontology International Volume: 該当なし Issue: 10 Pages: 1527-1533
  • DOI: 10.1111/ggi.12910
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Presentation] Impact of sedentary time on chronic kidney disease (CKD) and disability incidence in community-dwelling Japanese older adults: a 4-year prospective cohort study (2019)
  • Author(s): Sungchul Lee, Sangyoon Lee, Seongryu Bae, Kazuhiro Harada, Songee Jung, Keitaro Makino, Hiroyuki Shimada
  • Organizer: ECSS
  • Int'l Joint Research
• [Presentation] 日本高齢者における慢性腎臓病（CKD）の回復率と関連要因－4年間の前向き研究 (2018)
  • Author(s): 李成喆 李相侖 裵成琉 鄭松伊 牧野圭太郎 新海陽平 島田裕之
  • Organizer: 日本老年医学会
• [Presentation] Relationship between the Visceral Fat Accumulation and kidney function without diabetes mellitus in Japanese older adults. (2018)
  • Author(s): Sungchul Leea, Seongryu Bae, Kazuhiro Harada, Songee Jung, Keitaro Makino, Sangyoon Lee, Hiroyuki Shimada
  • Organizer: 韓国体育学会
  • Int'l Joint Research
• [Presentation] The relationship between kidney function and social frailty in community-dwelling older Japanese (2018)
  • Author(s): Sung chul Lee, Seongryu Bae, Songee Jung, Keitaro Makino, Sangyoon Lee, Hiroyuki Shimada
  • Organizer: Aging and Rejuvenation Conference
  • Int'l Joint Research
• [Presentation] The relationship between social frailty and kidney function decline in community-dwelling older Japanese (2017)
  • Author(s): SungChul Lee, Sangyoon Lee, Seongryu Bae, Songee Jung, Keitaro Makino, Yohei Shinkai, Hiroyuki Shimada
  • Organizer: 3rd Asian Conference for Frailty and Sarcopenia
  • Int'l Joint Research
• [Presentation] Impact of Sedentary time with Decreasing Chronic Kidney Function on Disability in Community-Dwelling Japanese older adults: 4-year prospective cohort study (2017)
  • Author(s): SungChul Lee, Sangyoon Lee, Seongryu Bae, Hyuma Makizako, Takehiko Doi, Kazuhiro Harada, Kota Tsutsumimoto, Ryo Hotta, Sho Nakakubo, Kenji Harada, Songee Jung, Masakazu Imaoka, Keitaro Makino, Hyuntae Park, Hiroyuki Shimada
  • Organizer: ECSS
  • Int'l Joint Research
• [Presentation] CKDにおける主観的健康感と要介護認定発生との関連 (2017)
  • Author(s): 李成喆, 李相侖, 裵成琉, 土井剛彦, 原田和弘, 堀田亮, 鄭松伊, 今岡真和, 鈴木隆雄, 島田裕之
  • Organizer: 日本老年医学会
• [Presentation] 地域在住の非糖尿病高齢者を対象とした慢性腎臓病とフレイルとの関連 (2017)
  • Author(s): 李成喆, 李相侖, 裵成琉, 牧迫飛雄馬, 中窪翔, 堤本広大, 原田健次, 鄭松伊, 今岡真和, 島田裕之
  • Organizer: 日本老年医学会