Longitudinal epidemiological study on the onset of brain atrophy and dementia due to physical, intellectual and social activity participation of older adults
| Project/Area Number |
17K01611
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Rehabilitation science/Welfare engineering
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| Research Institution | National Center for Geriatrics and Gerontology |
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Principal Investigator |
Lee Sangyoon 国立研究開発法人国立長寿医療研究センター, 老年学・社会科学研究センター, 室長 (90466194)
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| Project Period (FY) |
2017-04-01 – 2020-03-31
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| Project Status |
Completed (Fiscal Year 2019)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2019: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2018: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Keywords | 身体知的社会活動 / 認知機能 / 脳萎縮 / 活動量 / 身体活動量 / 高齢者の身体、知的、社会活動 / 活動量計 / 日常生活活動 / 認知症 / 身体・知的・社会活動 / 認知症発症 / 高齢者 / 活動的ライフスタイル |
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| Outline of Final Research Achievements |
In this study, we investigate the relationship between objectively measured activity status and cerebral atrophy and cognitive function using community-based outdoor activities. The subjects were older adults who participated in the health check-up and MRI examination and were able to objectively measure the amount of activity in daily life and the outdoor activity status (physical, intellectual, and social activities) using an accelerator. Approximately 4 years later, MRI and cognitive function tests were performed to analyze daily activity status, brain atrophy, and and longitudinal changes in cognitive function.
As a result of this research, it was shown that participation in various activity improve a daily physical activity and cognitive function. In addition, the progression of brain atrophy was observed with aging, indicating that the daily activity implementation may differ by age. We suggested that participation in activities may reduce cognitive decline.
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| Academic Significance and Societal Importance of the Research Achievements |
認知症の危険因子として、日常生活における不活動（inactivity）が指摘されているが、地域に多く存在する身体・知的・社会活動の有効性は明らかにされていない。本研究により、活動実施体制は年代別に異なること、また、多様な活動実施が認知機能の低下を抑制される可能性が示唆された。非薬物的な認知症予防方法として、地域密着型の戸外活動を用いた検討により、認知症予防に有効であるライフスタイルの基礎資料の提案が可能と考える。
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Report
(4 results)
Research Products
(40 results)
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[Presentation] 介護予防を目的としたセルフモニタリングの効果検証：ランダム化比較試験2019
Author(s)
島田裕之, 李相侖, 牧野圭太郎, 裵成琉, 新海陽平, 千葉一平, 片山脩, 原田健次, 山城由華吏, 高柳直人, 須藤元喜, 仁木佳文
Organizer
第9回日本認知症予防学会学術集会
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