Establishment of methodology for controlling postprandial blood sugar to regulate free-water in intestinal contents for clinical application
Project/Area Number |
17K01863
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Applied health science
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Research Institution | Koriyama Women's University (2018-2019) Fukuoka Women's University (2017) |
Principal Investigator |
Takahashi Toru 郡山女子大学, 家政学部, 准教授 (80324292)
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Co-Investigator(Kenkyū-buntansha) |
久保 金弥 名古屋女子大学, 健康科学部, 教授 (00329492)
安細 敏弘 九州歯科大学, 歯学部, 教授 (80244789)
小野塚 実 神奈川歯科大学, 歯学部, 名誉教授 (90084780)
徳永 美希 神奈川県立保健福祉大学, 保健福祉学部, 助教 (90610238)
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Project Period (FY) |
2017-04-01 – 2020-03-31
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Project Status |
Completed (Fiscal Year 2019)
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Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2019: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2018: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
|
Keywords | 自由水 / 水の拡散係数 / グルコースの拡散係数 / 消化管内容物 / 食後血糖 / 吸収速度 / 消化管内容物の移動 / 咀嚼物 / 粘度 / 飯 / 糖の拡散係数 / ベイジアンネットワーク / 唾液 / 小腸 / 物性 |
Outline of Final Research Achievements |
Number of persons with Diabetes mellitus were more than 3 million in Japan. High glucose levels in blood increase risk of cancer and evoke cognitive impairment. Thus, controlling glucose levels in blood would be a significant for people in Japan. Glucose levels in blood depends on absorption rate of glucose in the small intestine. The present study revealed a key factor to control absorption rate of glucose. The study suggests that the key factor to control absorption rate of glucose was free water levels in digesta in the small intestine.
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Academic Significance and Societal Importance of the Research Achievements |
The present study suggests that the key factor to control absorption rate of glucose was free water levels in digesta in the small intestine. If free water levels in digesta in the small intestine can be controlled, we can regulate glucose levels in blood.
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Report
(4 results)
Research Products
(32 results)
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[Journal Article] Increased subjective distaste and altered insula activity to umami in patients with bulimia nervosa2017
Author(s)
R.Setsu, Y. Hirano, M.Tokunaga, T. Takahashi, N. Numata, K. Matsumoto, Y. Masuda, D. Matsuzawa, M.Iyo, E. Shimizu, M. Nakazato
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Journal Title
Front Psychiatry
Volume: 8
Pages: 172-172
Related Report
Peer Reviewed
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[Journal Article] Relationships between pathologic subjective halitosis, olfactory reference syndrome, and social anxiety in young Japanese women2017
Author(s)
Miho Tsuruta, Toru Takahashi, Miki Tokunaga, Masanori Iwasaki, Shota Kataoka, Satoko Kakuta, Inho Soh, Shuji Awano, Hiromi Hirata, Masaharu Kagawa and Toshihiro Ansai
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Journal Title
BMC Psychology
Volume: 14
Issue: 1
Pages: 1-1
DOI
Related Report
Peer Reviewed / Open Access
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[Presentation] Dietary Fiber2019
Author(s)
T. Takahashi
Organizer
19th World Congress on Clinical Nutrition, Armedabad, India
Related Report
Int'l Joint Research / Invited
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