| Project/Area Number |
17K01989
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Basic / Social brain science
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| Research Institution | Keio University |
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Principal Investigator |
Jimura Koji 慶應義塾大学, 理工学部(矢上), 准教授 (80431766)
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| Co-Investigator(Kenkyū-buntansha) |
中原 潔 高知工科大学, 情報学群, 教授 (50372363)
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| Project Period (FY) |
2017-04-01 – 2020-03-31
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| Project Status |
Completed (Fiscal Year 2019)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2019: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2018: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2017: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 異時的意思決定 / 自己制御 / 機能的MRI / 報酬 / 報酬探索 / 遅延報酬 / 前頭前野 / 神経科学 / 認知科学 |
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| Outline of Final Research Achievements |
In the current study, we aimed to explore neural mechanisms for the formation of self-controlled choice preference and measured brain activity using fMRI while human participants performed a choice task for real liquid rewards. While they were awaiting a future reward, the anterior prefrontal cortex showed dynamics signals that reflected utility of anticipation, which was enhanced in self-controlled individuals. When the anterior prefrontal activity was increased, activity in the ventral striatum was diminished; this tendency was also enhanced in self-controlled individuals. On the other hand, during consumption of a liquid reward, reduced activity in ventral striatum was associated with subsequent self-controlled choice.
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| Academic Significance and Societal Importance of the Research Achievements |
将来に起こる好ましい出来事を期待することは，脳がもつ重要な機能であり，自己制御のある選択を可能にする．しかし，自己制御のある選択が，いつ，どのように形成されているかはよくわかっていない．そこで，本研究は，遅延する液体報酬を経験・選択する際の脳活動を計測し，自己制御の選択指向がどのように形成されるかを調べた．本研究で発見された前頭前野の信号の時間的特徴は，将来の報酬を待つことの楽しさが，自己制御の選択指向の形成に関わっていること示唆している．
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