| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2019: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2018: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2017: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Outline of Final Research Achievements |
In this study, we report the preparation and characterization of novel functional nanomaterials fabricated from peptide-based multiblock copolymers. Spider silk-mimicked multiblock copolymers composed of self-assembling oligopeptides and poly(propylene glycol) were newly synthesized by combining the solid phase peptide synthesis with the polyaddition reaction. Self-supporting nanofilms and nanofibers of these copolymers were successfully obtained by spin-coating and electro-spinning methods, respectively. These nanofilms (nanofibers) showed the high mechanical property, self-healing character and good cell adhesive properties. In addition, we developed a facile and versatile strategy for preparing functional multiblock copolymers composed of alternately aligned sequential peptides and well-defined vinyl polymers with a narrow polydispersity.
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