Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2019: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2018: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2017: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
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Outline of Final Research Achievements |
Dissolution experiments of amorphous silica by interaction of amino acid were performed to evaluate the effect of biological organic molecules on the dissolution rates of amorphous silica. Additionally, adsorption experiments of amino acids on the amorphous silica surface were carried out to conform the adsorption affinity of amino acids for the amorphous silica. The dissolution experiments were conducted by the flow through system using 0.1 g of amorphous silica and 10 mmol/L amino acids solutions (Cys, Asn, Ser, Trp, Ala, Thr, His, Lys, Arg)at constant solution pH of 6, 5, 4. Results indicated that the basic amino acids (His, Lys, Arg) increased the dissolution rate by about 8-fold, and other amino acids showed about 2-fold increase. These enhancement of dissolution by interaction with amino acids was consistent with the concentrations of cationic species of amino acids molecules, and also with the adsorption affinity of amino acids for the amorphous silica surface..
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