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Numerical Study on Mechanical Effects of Cavitation in High-intensity Focused Ultrasound

Research Project

Project/Area Number 17K06170
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Fluid engineering
Research InstitutionNihon University

Principal Investigator

OKITA Kohei  日本大学, 生産工学部, 准教授 (20401135)

Project Period (FY) 2017-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2019: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2018: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2017: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywordsキャビテーション / 医用超音波 / 気泡力学 / 流体工学 / バイオ流体力学
Outline of Final Research Achievements

Collapse of cavitation bubble clouds enhances the mechanical effects of cavitation on therapeutic ultrasound treatments. A software application was developed to clarify the spatial distribution as well as nonlinear behavior of cavitation bubble clouds in a focused ultrasound field. As the results, the effects of the heat and mass transfer through the bubble interface and the translation motion of bubbles on the distribution of the cavitation bubble cloud were clarified by the present numerical simulation. In addition, irradiation parameters of ultrasound for the safe and efficient cavitation-enhanced focused ultrasound treatment werer studied.

Academic Significance and Societal Importance of the Research Achievements

キャビテーション気泡の界面における熱・物質移動や気泡の並進運動といったミクロな物理現象や様々な物性が,マクロな集束超音波音場におけるキャビテーション気泡群の空間分布とその崩壊に与える影響に関する知見は,キャビテーションを援用した集束超音波治療の安全性の向上と高効率化において学術的に重要であり,本研究で開発されたソフトウェアアプリケーションは次世代の医用超音波技術の開発に貢献するものである.

Report

(4 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Research-status Report
  • 2017 Research-status Report
  • Research Products

    (15 results)

All 2019 2018 2017

All Journal Article (5 results) (of which Peer Reviewed: 3 results,  Open Access: 4 results) Presentation (10 results) (of which Int'l Joint Research: 6 results,  Invited: 3 results)

  • [Journal Article] Effects of breast structure on high-intensity focused ultrasound focal error2018

    • Author(s)
      Kohei Okita, Ryuta Narumi, Takashi Azuma, Hidemi Furusawa, Junichi Shidooka, Shu Takagi and Yoichiro Matsumoto
    • Journal Title

      Journal of Therapeutic Ultrasound

      Volume: 6:4 Issue: 1

    • DOI

      10.1186/s40349-018-0111-9

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Numerical study on growth and collapse of cloud cavitation in a focused ultrasound field2018

    • Author(s)
      Kohei Okita
    • Journal Title

      Proc. Mtgs. Acoust.

      Volume: 34 Pages: 020002-020002

    • DOI

      10.1121/2.0000907

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Influence of Collapse of Cavitation Bubble Cloud on Erosion of Solid Surface in Hydraulic Machinery2018

    • Author(s)
      Kohei Okita, Yuusuke Miyamoto, Teruyuki Furukawa, Shinobu Nagura, Shu Takagi, Hiroharu Kato
    • Journal Title

      Proceedings of the 10the Symposium on Cavitation(CAV2018)

      Volume: - Pages: 542-545

    • DOI

      10.1115/1.861851_ch103

    • ISBN
      9780791861851
    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 超音波によるバブルリポソームの制御に関するシミュレーション手法の開発2017

    • Author(s)
      速水 尚,伊井仁志,沖田浩平,高木 周
    • Journal Title

      ながれ

      Volume: 36 Pages: 93-100

    • Related Report
      2017 Research-status Report
    • Open Access
  • [Journal Article] 強力集束超音波による低侵襲治療HIFUシミュレーション2017

    • Author(s)
      沖田浩平
    • Journal Title

      超音波テクノ

      Volume: 29 Pages: 13-17

    • Related Report
      2017 Research-status Report
  • [Presentation] Effect of rectified diffusion on the growth of ca vitation bubble clouds in a focused ultrasound field2019

    • Author(s)
      Kohei Okita
    • Organizer
      10th International Conference on Multiphase Flow, ICMF 2019, Rio de Janeiro, Brazil, May 19-24
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 集束超音波音場に生じるクラウドキャビテーションの成長と崩壊に関する数値解析2018

    • Author(s)
      沖田浩平
    • Organizer
      キャビテーションに関するシンポジウム(第19回)
    • Related Report
      2018 Research-status Report
  • [Presentation] 超音波水槽内の反射を低減させる吸音材表面の加工法についての検討2018

    • Author(s)
      中村裕志,大谷修司,沖田浩平,葭仲潔,佐々木明,小関義彦
    • Organizer
      第17回日本超音波治療研究会
    • Related Report
      2018 Research-status Report
  • [Presentation] 集束超音波治療に対するシミュレーション技術開発2018

    • Author(s)
      沖田浩平
    • Organizer
      日本機械学会第31回バイオエンジニアリング講演会
    • Related Report
      2018 Research-status Report
    • Invited
  • [Presentation] Numerical Study on Growth and Collapse of Cloud Cavitation in a Focused Ultrasound Field2018

    • Author(s)
      Kohei Okita
    • Organizer
      21st International Symposium on Nonlinear Acoustics
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research
  • [Presentation] Influence of Collapse of Cavitation Bubble Cloud on Erosion of Solid Surface in Hydraulic Machinery2018

    • Author(s)
      Kohei Okita, Yuusuke Miyamoto, Teruyuki Furukawa, Shinobu Nagura, Shu Takagi, Hiroharu Kato
    • Organizer
      The 10the International Symposium on Cavitation (CAV2018)
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research
  • [Presentation] Numerical Simulation of Cavitation-enhanced HIFU Therapy2017

    • Author(s)
      K. Okita, S. Takagi, Y. Matsumoto
    • Organizer
      19h International Conference on Finite Elements in Flow Problems - FEF 2017
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Multiscale simulations for fluid structure interaction problems with biomedical applications2017

    • Author(s)
      S. Takagi, K. Shimizu, S Ii, K. Sugiyama, K Okita
    • Organizer
      The 4th Symposium on Fluid-Structure-Sound Interactions and Control
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Influence of cavitation bubble growth by rectified diffusion on cavitation-enchanced HIFU2017

    • Author(s)
      K. Okita, K. Sugiyama, S. Takagi, Y. Matsumoto
    • Organizer
      70th Annual Meeting of the APS Division of Fluid Dynamics
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] 集束超音波治療におけるキャビテーション気泡の成長と加熱効率2017

    • Author(s)
      沖田浩平,杉山和靖,髙木周,松本洋一郎
    • Organizer
      日本流体力学年会2017
    • Related Report
      2017 Research-status Report

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Published: 2017-04-28   Modified: 2021-02-19  

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