| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2019: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2018: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2017: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Outline of Final Research Achievements |
This study aimed to develop a nano-watt grade bio-calorimeter which measures the metabolic heat of a single individual bio sample. Following three development has been performed, improvement of sensitivity of the heat sensor with the MEMS technology, a noise reduction of the amplifier circuit with four parallel instrumentation amplifiers, and improvement of stability of a four layer thermostatic chambers with a digital PI control technique.
As a result, it was shown that the growth process of yeast and the hatching process of a single egg of brine shrimp can be measured continuously for more than 100 hours, and the heat of metabolism can be measured in the range of 10 nano-watt level to 10 miro-watt level.
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