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Measurements of piezoelectric properties in cancellous bone under ultrasound irradiation

Research Project

Project/Area Number 17K06479
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Measurement engineering
Research InstitutionAkashi National College of Technology

Principal Investigator

Hosokawa Atsushi  明石工業高等専門学校, 電気情報工学科, 准教授 (00321456)

Project Period (FY) 2017-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2019: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2018: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2017: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Keywords海綿骨 / 圧電特性 / 超音波 / 間隙流体 / 骨梁構造 / 圧電信号 / 電極 / 数値シミュレーション
Outline of Final Research Achievements

In this study, the piezoelectric properties of cancellous bone in the ultrasound (high-frequency) region were experimentally investigated. First, "a piezoelectric cell," which is an ultrasonic sensor using a cancellous bone specimen as a piezoelectric element was developed and improved,and a method for observing piezoelectric signals generated in cancellous bone by ultrasoound irradiation could be established. Next, using the piezoelectric cell, the piezoelectric signal in cancellous bone was measured, and the piezoelectric properties were investigated. Concretely, the difference in the piezoelectric signal owing to the fluid filling the pores in cancellous bone was shown with the relationship with the ultrasound signal propagating through the bone. Moreover, the effect of the trabecular orientation in cancellous bone on the piezoelectric signal were shown.

Academic Significance and Societal Importance of the Research Achievements

現在、超音波照射による骨折治療が行われているが、その物理的(電気・機械的)メカニズムは不明なままである。骨の生成骨には骨が有する圧電特性が関係すると考えられているが、超音波(高周波)帯域における骨の圧電特性は十分に分かっていない。特に、多孔性構造を有する海綿骨における圧電特性については、ほとんど未知であると言える。本研究で明らかにした海綿骨の圧電特性は、海綿骨生成の物理メカニズムの解明の一助となることが期待できる。最終的には、海綿骨を多く含む関節骨における骨折の効率的な治癒方法の実現につながると考えられる。

Report

(4 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Research-status Report
  • 2017 Research-status Report
  • Research Products

    (21 results)

All 2020 2019 2018 2017

All Journal Article (9 results) (of which Open Access: 4 results,  Peer Reviewed: 5 results) Presentation (12 results) (of which Int'l Joint Research: 5 results)

  • [Journal Article] Numerical analysis of backscatter properties of fast and slow waves in cancellous bone2020

    • Author(s)
      Atsushi Hosokawa
    • Journal Title

      Japanese Journal of Applied Physics

      Volume: 59 Issue: 3 Pages: 036504-036504

    • DOI

      10.35848/1347-4065/ab7720

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Change of piezoelectric signal in cancellous bone with ultrasound irradiation angle2020

    • Author(s)
      Atsushi Hosokawa
    • Journal Title

      Japanese Journal of Applied Physics

      Volume: 59 Issue: SK Pages: SKKE03-SKKE03

    • DOI

      10.35848/1347-4065/ab7f56

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Experimental observations of piezoelectric signals generated in cancellous bone at megahertz frequencies2019

    • Author(s)
      Atsushi Hosokawa
    • Journal Title

      Proceedings of Meetings on Acoustics

      Volume: 38 Pages: 020001-020001

    • DOI

      10.1121/2.0001055

    • Related Report
      2019 Annual Research Report
    • Open Access
  • [Journal Article] Frequency dependence of the piezoelectric signal generated in cancellous bone by Ultrasound irradiation2019

    • Author(s)
      Atsushi Hosokawa
    • Journal Title

      Proceedings of Meetings on Acoustics

      Volume: -

    • Related Report
      2018 Research-status Report
    • Open Access
  • [Journal Article] Observations of experimental and numerical waveforms of piezoelectric2018

    • Author(s)
      Atsushi Hosokawa
    • Journal Title

      Japanese Journal of Applied Physics

      Volume: 57 Issue: 7S1 Pages: 07LF06-07LF06

    • DOI

      10.7567/jjap.57.07lf06

    • Related Report
      2018 Research-status Report
    • Peer Reviewed
  • [Journal Article] 超音波照射下での海綿骨における圧電信号の実験的観測=海綿骨で作製した圧電セルによる超音波の受波=2018

    • Author(s)
      細川篤
    • Journal Title

      超音波TECHNO

      Volume: 30 Pages: 94-97

    • Related Report
      2017 Research-status Report
  • [Journal Article] Observations of experimental and numerical waveforms of piezoelectric signals generated in bovine cancellous bone by ultrasound waves2018

    • Author(s)
      Atsuhi Hosokawa
    • Journal Title

      Japanease Journal of Applied Physics

      Volume: in press

    • NAID

      210000149343

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Investigation of piezoelectric anisotropy of bovine cortical bone at an ultrasound frequency by coupling an experiment and a simulation2017

    • Author(s)
      A. Hosokawa
    • Journal Title

      The Journal of the Acoustical Society of America

      Volume: 142 Issue: 2 Pages: EL184-EL189

    • DOI

      10.1121/1.4996909

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Structural dependence of piezoelectric signal in cancellous bone at an ultrasound frequency2017

    • Author(s)
      Atsushi Hosokawa
    • Journal Title

      Proceedings of Meetings on Acoustics

      Volume: 32 Pages: 020001-020001

    • DOI

      10.1121/2.0000687

    • Related Report
      2017 Research-status Report
    • Open Access
  • [Presentation] 海綿骨における圧電信号の照射超音波周波数による変化2020

    • Author(s)
      細川篤
    • Organizer
      2020年電子情報通信学会総合大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 水で飽和した海綿骨で発生する圧電信号の観測2019

    • Author(s)
      細川篤, 壁下育弥
    • Organizer
      2019年電子情報通信学会総合大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Experimental observations of piezoelectric signals generated in water-saturated cancellous bone by ultrasound irradiation2019

    • Author(s)
      Atsushi Hosokawa
    • Organizer
      8th International Symposium on Ultrasounic Characterization of Bone
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Experimental observations of piezoelectric signals generated in cancellous bone at megahertz frequencies2019

    • Author(s)
      Atsushi Hosokawa
    • Organizer
      2019 International Congress on Ultrasonics
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Effect of ultrasound direction on piezoelectric signal generated in cancellous bone2019

    • Author(s)
      Atsushi Hosokawa
    • Organizer
      The 40th Symposium on UltraSonic Electronics
    • Related Report
      2019 Annual Research Report
  • [Presentation] 水で飽和した海綿骨で発生する圧電信号の観測2019

    • Author(s)
      細川篤, 壁下育弥
    • Organizer
      電子情報通信学会2019年総合大会
    • Related Report
      2018 Research-status Report
  • [Presentation] Effect of pore fluid on piezoelectric signal generated in cancellous bone by ultrasound irradiation2018

    • Author(s)
      Atsushi Hosokawa
    • Organizer
      The 39th Symposium on UltraSonic Electronics (USE2018)
    • Related Report
      2018 Research-status Report
  • [Presentation] Frequency dependence of the piezoelectric signal generated in cancellous bone by Ultrasound irradiation2018

    • Author(s)
      Atsushi Hosokawa
    • Organizer
      13th Western Pacific Acoustics Conference (WESPAC 2018)
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research
  • [Presentation] 海綿骨を用いた超音波センサの電極に関する検討2018

    • Author(s)
      壁下育弥, 細川篤
    • Organizer
      2018年電子情報通信学会総合大会
    • Related Report
      2017 Research-status Report
  • [Presentation] Estimation of piezoelectric sensitivity at an ultrasound frequency in bovine cancellous bone2017

    • Author(s)
      Atsushi Hosokawa
    • Organizer
      21st International Bone Densitometry Workshop (IBDW) and 7th European Symposium on Ultrasonic Characterization of Bone (ESUCB)
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Experimental and numerical observations of piezoelectric signal generated in cancellous bone by an ultrasound wave2017

    • Author(s)
      Atsushi Hosokawa
    • Organizer
      The 38th Symposium on UltraSonic Electronics (USE2017)
    • Related Report
      2017 Research-status Report
  • [Presentation] Structural dependence of piezoelectric signal in cancellous bone at an ultrasound frequency2017

    • Author(s)
      Atsushi Hosokawa
    • Organizer
      2017 International Congress on Ultrasonics (ICU)
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research

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Published: 2017-04-28   Modified: 2021-02-19  

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