| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2019: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2018: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2017: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Outline of Final Research Achievements |
The variation in ORAC was relatively low in brackish water clam Corbicula japonica with shell lengths between 19～25mm. Gills were more appropriate organs for detecting antioxidant effects. A simple modified method for scope for growth (SFG) assay of C. japonica was developed using the carbon mass balance estimated from three experiments: a clearance experiment, an excretion experiment and a respiration experiment. Oxidative stress as biochemical-level response and SFG as individual-level response were examined in C. japonica exposed to 5× dilution municipal wastewater and its components. An integrated biomarker responses (IBR) index estimating from the responses of oxidative stress makers used revealed that the most significant stressor was dissolved matters in wastewater. Further, a negative correlation was found between IBR and SFG. We conclude that SFG can be a useful indicator to interpret the response of oxidative stress markers in C. japonica.
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