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Systematic measurements of production cross sections for medical radioisotopes

Research Project

Project/Area Number 17K07004
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Nuclear engineering
Research InstitutionHokkaido University

Principal Investigator

Aikawa Masayuki  北海道大学, 理学研究院, 教授 (00374736)

Co-Investigator(Kenkyū-buntansha) 右近 直之  福島県立医科大学, 公私立大学の部局等, 助教 (70792985)
Project Period (FY) 2017-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2019: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2018: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2017: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Keywords放射化断面積 / 医療用放射性同位体 / 核反応断面積 / 放射化法 / 放射性同位体
Outline of Final Research Achievements

Radioisotopes are available for a variety of applications. One of the application fields is the medicine, including radiotherapy and diagnostics of cancers. Production cross sections and yields of such radioisotopes are essential information for the application. However, there still exist a lack of data and data with large uncertainties in many reactions. Therefore, we performed experiments to obtain more accurate and reliable data. In the project, we focused on charged-particle-induced reactions using proton, deuteron and alpha-particles. As a result, we could publish 15 papers in international scientific journals.

Academic Significance and Societal Importance of the Research Achievements

医学分野で利用されている放射性同位元素の生成に不可欠な情報の一つである、核反応断面積を取得した。本事業では、荷電粒子入射反応に着目し、陽子、重陽子、およびアルファ粒子入射反応による生成断面積測定を実施した。この成果により、医療で用いられていることが検討されている放射性同位体の生成について知見が深まり、実現可能性についてより具体的に考察することが可能となった。

Report

(4 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Research-status Report
  • 2017 Research-status Report
  • Research Products

    (25 results)

All 2020 2019 2018 Other

All Int'l Joint Research (3 results) Journal Article (15 results) (of which Int'l Joint Research: 10 results,  Peer Reviewed: 15 results) Presentation (7 results) (of which Int'l Joint Research: 3 results,  Invited: 1 results)

  • [Int'l Joint Research] ハンガリー原子核研究所(ハンガリー)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] ハンガリー原子核研究所(ハンガリー)

    • Related Report
      2018 Research-status Report
  • [Int'l Joint Research] ハンガリー原子核研究所(ハンガリー)

    • Related Report
      2017 Research-status Report
  • [Journal Article] Production cross sections of 68Ga and radioactive by-products in deuteron-induced reactions on natural zinc2020

    • Author(s)
      Zolbadral Tsoodol, Masayuki Aikawa, Ichinkhorloo Dagvadorj, Tegshjargal Khishigjargal, Namsrai Javkhlantugs, Yukiko Komori, Hiromitsu Haba
    • Journal Title

      Applied Radiation and Isotopes

      Volume: 159 Pages: 109095-109095

    • DOI

      10.1016/j.apradiso.2020.109095

    • NAID

      120007193353

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Production cross sections of 169Yb by the proton-induced reaction on 169Tm2020

    • Author(s)
      Moemi Saito, Masayuki Aikawa, Tomohiro Murata, Yukiko Komori, Hiromitsu Haba, Sandor Takacs, Ferenc Ditroi, Zoltan Szucs
    • Journal Title

      Nuclear Instruments and Methods in Physics Research Section B

      Volume: 471 Pages: 13-16

    • DOI

      10.1016/j.nimb.2020.03.019

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Production cross sections of ytterbium and thulium radioisotopes in alpha-induced nuclear reactions on natural erbium2019

    • Author(s)
      Saito Moemi、Aikawa Masayuki、Sakaguchi Michiya、Ukon Naoyuki、Komori Yukiko、Haba Hiromitsu
    • Journal Title

      Applied Radiation and Isotopes

      Volume: 154 Pages: 108874-108874

    • DOI

      10.1016/j.apradiso.2019.108874

    • NAID

      120007140373

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Activation cross sections of dysprosium-157,159 and terbium-160 radioisotopes from the deuteron-induced reactions on terbium-159 up to 24?MeV2019

    • Author(s)
      Ichinkhorloo Dagvadorj、Aikawa Masayuki、Zolbadral Tsoodol、Komori Yukiko、Haba Hiromitsu
    • Journal Title

      Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms

      Volume: 461 Pages: 102-104

    • DOI

      10.1016/j.nimb.2019.09.037

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Excitation function measurement for zirconium-89 and niobium-90 production using alpha -induced reactions on yttrium-892019

    • Author(s)
      *T. Murata, M. Aikawa, M. Saito, H. Haba, Y. Komori, N. Ukon, S. Takacs, F. Ditroi
    • Journal Title

      Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms

      Volume: 458 Pages: 21-27

    • DOI

      10.1016/j.nimb.2019.07.043

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Activation cross sections of alpha-induced reactions on natural ytterbium up to 50?MeV2019

    • Author(s)
      Saito Moemi、Aikawa Masayuki、Murata Tomohiro、Ukon Naoyuki、Komori Yukiko、Haba Hiromitsu、S. Takacs
    • Journal Title

      Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms

      Volume: 453 Pages: 15-21

    • DOI

      10.1016/j.nimb.2019.05.074

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Study of secondary implantation of radioisotopes during alpha-particle irradiation2019

    • Author(s)
      Enrico Corniani , F. Ditroi, S. Takacs, Hiromitsu Haba, Yukiko Komori, Masayuki Aikawa, Moemi Saito & Tomonori Murata
    • Journal Title

      Journal of Radioanalytical and Nuclear Chemistry

      Volume: 320 Issue: 3 Pages: 813-822

    • DOI

      10.1007/s10967-019-06527-4

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Activation cross sections of alpha-particle induced nuclear reactions on natural palladium2019

    • Author(s)
      Aikawa M.、Saito M.、Komori Y.、Haba H.、Tak?cs S.、Ditr?i F.、Sz?cs Z.
    • Journal Title

      Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms

      Volume: 449 Pages: 99-104

    • DOI

      10.1016/j.nimb.2019.04.066

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Production cross sections of Mo, Nb and Zr radioisotopes from α-induced reaction on natZr2019

    • Author(s)
      T. Murata, M. Aikawa, M. Saito, N. Ukon, Y. Komori, H. Haba, S.Takacs
    • Journal Title

      Applied Radiation and Isotopes

      Volume: 144 Pages: 47-53

    • DOI

      10.1016/j.apradiso.2018.11.012

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Activation cross sections of deuteron-induced reactions on niobium up to 24 MeV2018

    • Author(s)
      M. Aikawa, Y. Komori, H. Haba
    • Journal Title

      Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms

      Volume: 436 Pages: 217-220

    • DOI

      10.1016/j.nimb.2018.09.039

    • Related Report
      2018 Research-status Report
    • Peer Reviewed
  • [Journal Article] Investigation of alpha particle induced reactions on natural silver in the 40-50 MeV energy range2018

    • Author(s)
      F. Ditroi, S. Takacs, H. Haba, Y. Komori, M. Aikawa, M. Saito, T. Murata
    • Journal Title

      Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms

      Volume: 436 Pages: 119-129

    • DOI

      10.1016/j.nimb.2018.09.018

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Activation cross sections of α-induced reactions on natZn for Ge and Ga production2018

    • Author(s)
      M. Aikawa, M. Saito, S. Ebata, Y. Komori, H. Haba
    • Journal Title

      Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms

      Volume: 427 Pages: 91-94

    • DOI

      10.1016/j.nimb.2018.05.006

    • Related Report
      2018 Research-status Report
    • Peer Reviewed
  • [Journal Article] Activation cross sections of alpha-induced reactions on natIn for 117mSn production2018

    • Author(s)
      M. Aikawa, M. Saito, N. Ukon, Y. Komori, H. Haba
    • Journal Title

      Nuclear Instruments and Methods in Physics Research Section B

      Volume: 426 Pages: 18-21

    • DOI

      10.1016/j.nimb.2018.04.023

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Measurement of activation cross sections of alpha particle induced reactions on iridium up to an energy of 50 MeV2018

    • Author(s)
      S. Takacs, F. Ditroi, Z. Szucs, M. Aikawa, H. Haba, Y. Komori, M. Saito
    • Journal Title

      Applied Radiation and Isotopes

      Volume: 136 Pages: 133-142

    • DOI

      10.1016/j.apradiso.2018.02.023

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Production cross sections of deuteron-induced reactions on natural palladium for Ag isotopes2018

    • Author(s)
      Naoyuki Ukon, Masayuki Aikawa, Yukiko Komori, Hiromitsu Haba
    • Journal Title

      Nuclear Instruments and Methods in Physics Research Section B

      Volume: 426 Pages: 13-17

    • DOI

      10.1016/j.nimb.2018.04.019

    • NAID

      120006864484

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Presentation] Production of 169Yb by the proton-induced reaction on 169Tm2019

    • Author(s)
      Moemi Saito, Masayuki Aikawa, Tomohiro Murata, Yukiko Komori, Hiromitsu Haba, Sandor Takacs, Ferenc Ditroi, Zoltan Szucs
    • Organizer
      2019年度核データ研究会
    • Related Report
      2019 Annual Research Report
  • [Presentation] GALLIUM-68 PRODUCTION IN ZINC OXIDE NANOPARTICLES2019

    • Author(s)
      Masayuki AIKAWA
    • Organizer
      1st integrated conference on joint research program in Mongolia (ICJPM)
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] 89Y標的への重陽子入射反応による89Zr生成反応断面積2018

    • Author(s)
      M. Sakaguchi, M. Aikawa, M. Saito, N. Ukon, Y. Komori, H. Haba
    • Organizer
      2018年度核データ研究会
    • Related Report
      2018 Research-status Report
  • [Presentation] Systematic study on charged-particle-induced reactions for medical radioisotope production2018

    • Author(s)
      M. Aikawa, M. Saito, T. Murata, M. Sakaguchi
    • Organizer
      The 9th AASPP Workshop on Asian Nuclear Reaction Database Development
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research
  • [Presentation] 99Mo production from alpha-induced reaction on 96Zr2018

    • Author(s)
      T. Murata, M. Aikawa, M. Saito, N. Ukon, Y. Komori, H. Haba, S. Takacs
    • Organizer
      18th Radiochemical Conference
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research
  • [Presentation] Zr標的へのアルファ粒子照射による99Moの励起関数測定2018

    • Author(s)
      村田朋大, 合川正幸, 齋藤萌美, 右近直之, 小森有希子, 羽場宏光, タカッチ サンドール
    • Organizer
      日本原子力学会2018年春の年会
    • Related Report
      2017 Research-status Report
  • [Presentation] natYbへの50 MeVアルファ粒子入射反応における177Luの生成断面積について2018

    • Author(s)
      齋藤萌美, 合川正幸, 村田朋大, 右近直之, 小森有希子, 羽場宏光, Sandor Takacs
    • Organizer
      日本原子力学会2018年春の年会
    • Related Report
      2017 Research-status Report

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Published: 2017-04-28   Modified: 2021-02-19  

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