| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2019: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2018: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2017: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Outline of Final Research Achievements |
We established a method to specifically concentrate and purify primary cilia-derived extracellular vesicles and established a cell line that does not specifically release primary cilia-derived extracellular vesicles, and succeeded in establishing an experimental system that can verify the physiological functions of primary cilia-derived extracellular vesicles. By making full use of these methods, we succeeded in finding that primary cilia-derived vesicles were actually taken up by the target cells and that the cell migration of the target cells was enhanced as a result. These methodologies and findings have been reported in international scientific journals, Japanese language science journals, and various academic conferences.
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