| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2019: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2018: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2017: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Outline of Final Research Achievements |
We analyzed the molecular mechanisms to affect nutritional signals during the larval period on developmental timing of Drosophila. We found that the signal goes in before the early stage of prepupa and that the mechanism may not be simple, although at least some of the Insulin and TOR pathway factors contribute to the pathway.
In the mechanism to determine prepupal period, we got results to suggest that Blimp-1 degrades in 26S proteasome identified by FBXO11 and that the short peptide Pri contributes in the degradation system.
We identified the promoter region of the FTZ-F1 gene which is expressed in the prothoracic gland during 3rd instar larva and got results to show that this region plays an important role to determine the 3rd instar larval period.
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