Molecular network of wound-induced dedifferentiation
| Project/Area Number |
17K07461
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Plant molecular biology/Plant physiology
|
|---|
| Research Institution | Institute of Physical and Chemical Research |
|---|
Principal Investigator |
Iwase Akira 国立研究開発法人理化学研究所, 環境資源科学研究センター, 研究員 (40553764)
|
|---|
| Project Period (FY) |
2017-04-01 – 2021-03-31
|
| Project Status |
Completed (Fiscal Year 2020)
|
| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2019: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2018: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2017: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
|
|---|
| Keywords | 傷害ストレス / 細胞リプログラミング / 脱分化 / 再分化 / 転写因子 / 遺伝子発現ネットワーク / 導管要素 / 病害応答 / カルス / 再生 / 幹細胞 / 維管束形成 / 防御応答 / 転写因子ネットワーク / 分化可塑性 / 分化全能性 / 遺伝子発現解析 / 傷害応答 / 分子ネットワーク |
|---|
| Outline of Final Research Achievements |
This study tried to elucidate which genes are involved in plants to induce cell dedifferentiation upon wounding stress. We focused on wound-inducible transcription factors and did comprehensive transcriptome analyses after injuring and after induction of the transcription factor. The results revealed that gene expression of other transcription factors known to be involved in tissue regeneration under tissue culture conditions are regulated by the transcription factor. Plus, genes involved in vascular bundle formation and disease response are regulated by the factor.
|
| Academic Significance and Societal Importance of the Research Achievements |
傷を受けた生物は、傷口において傷の修復や病原菌からの防御を行う必要があるが、植物も、傷害応答性のスイッチタンパク質によって再生から防御応答にわたるまで多岐に渡る生理現象を同時に引き起こしていることが明らかとなった。この解析から選抜されてきた遺伝子には、組織培養において再生を促進する機能を持つものや、病害ストレスから身を守るための機能を持つものが多く含まれていると考えられるため、これらの遺伝子の機能を利用した応用研究も期待される。
|
Report
(5 results)
Research Products
(18 results)
-
-
-
-
[Journal Article] WIND1 induces dynamic metabolomic reprogramming during regeneration in Brassica napus2018
Author(s)
Akira Iwase, Kento Mita, David S.Favero, Nobutaka Mitsuda, Ryosuke Sasaki, Makoto Kobayshi, Yumiko Takebayashi, Mikiko Kojima, Miyako Kusano, Akira Oikawa, Hitoshi Sakakibara, Kazuki Saito, Jun Imamura, Keiko Sugimoto
-
Journal Title
Developmental Biology
Volume: 442
Issue: 1
Pages: 40-52
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
-
[Journal Article] A Gene Regulatory Network for Cellular Reprogramming in Plant Regeneration2018
Author(s)
Ikeuchi M, Shibata M, Rymen B, Iwase A, Bagman AM, Watt L, Coleman D, Favero DS, Takahashi T, Ahnert SE, Brady SM, Sugimoto K
-
Journal Title
Plant and Cell Physiology
Volume: 59
Issue: 4
Pages: 770-782
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
-
[Journal Article] Wounding Triggers Callus Formation via Dynamic Hormonal and Transcriptional Changes2017
Author(s)
Ikeuchi M, Iwase A, Rymen B, Lambolez A, Kojima M, Takebayashi Y, Heyman J, Watanabe S, Seo M, De Veylder L, Sakakibara H, Sugimoto K
-
Journal Title
Plant Physiology
Volume: 175
Issue: 3
Pages: 1158-1174
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
-
-
-
-
-
-
-
-
-
-
-
-
