| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2019: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2018: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2017: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Outline of Final Research Achievements |
The feathers of birds are skin appendages composed of dead epidermal cells like mammalian hair. In chickens, there is a marked sex difference in the saddle feathers. In this study, we used this saddle feather as a model system to analyze the molecular mechanism of the formation of sex difference in the skin appendage. In addition, we analyzed the molecular mechanism of the late feathering widely used for autosexing of day-old chicks in hatcheries. Our results suggest that various hormone systems such as sex hormones and melanocortins cross-talk with each other to form proper feathers, and that slow feathering is caused by quantitative changes in prolactin signaling.
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