| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2019: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2018: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2017: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Outline of Final Research Achievements |
Resistance proteins are important intracellular receptors for plant immunity. The applicant has previously shown that the resistance protein Pit, an immune receptor for blast fungus, induces a defense response to the fungus through small GTPase OsRac1, a master regulator of rice. In this study, we found that Resistance protein Pit induces disease resistance to rice blast fungus by activating OsRac1 through a G-protein activator protein called OsSPK1. In addition, they identified three amino acids in the CC domain of Pit that are important for subcellular localization and function. These discoveries reveal the activation mechanism of resistance proteins that induce the strongest immune response in plants.
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