| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2019: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2018: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2017: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Outline of Final Research Achievements |
Plants produce a vast array of useful small molecules called secondary metabolites. Glycyrrhizin is a triterpenoid saponin produced only in roots and stolons of Glycyrrhiza species (licorice) in the legume family. It is widely used as medicines and natural sweetener. Besides glycyrrhizin, licorice also produces soyasaponins. Biosynthesis of saponins is strictly regulated as it is often limited in the specific organs or tissues, or induced in response to external or internal stimuli. However regulatory mechanism of triterpenoid biosynthesis is largely unknown. The objective of this research is to identify transcription factors (TFs) regulating saponins biosynthesis in licorice. We identified a bHLH-type TF able to activate transcription of soyasaponin biosynthetic genes. We also identified some candidate TFs potentially regulate glycyrrhizin biosynthetic genes.
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