• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Physiological and ecological functions of beta-tyrosine produced by Oryza sativa

Research Project

Project/Area Number 17K07770
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Bioorganic chemistry
Research InstitutionKyoto University

Principal Investigator

Mori Naoki  京都大学, 農学研究科, 教授 (30293913)

Co-Investigator(Kenkyū-buntansha) 寺石 政義  京都大学, 農学研究科, 准教授 (80378819)
Project Period (FY) 2017-04-01 – 2021-03-31
Project Status Completed (Fiscal Year 2020)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2020: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2019: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2018: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords非天然アミノ酸 / 根の伸長阻害 / アレロパシー活性 / beta-tyrosine / イネ / bets-tyrosine / beta-アミノ酸
Outline of Final Research Achievements

(1) (3R)- and (3S)-β-tyrosine showed inhibitory activity on Arabidopsis root elongation, whereas neither m-(3R)-β-tyrosine nor o-(3R)-β-tyrosine showed any inhibitory activity. The coexistence of an amino group at the β-position and a hydroxy group at the p-position in the benzene ring was required for the activity. (2) The accumulation of (R)-β-tyrosine in rice plants at different growth stages (3rd, 5th and 7th leaf stage) showed that (3R)-β-tyrosine accumulated after the 5th leaf stage. The highest accumulation of (3R)-β-tyrosine was observed in the fifth leaf of the fully expanded rice plants. The diurnal variation of (3R)-β-tyrosine accumulation in the fully expanded fifth leaf of rice was constant, unlike that of other amino acids. This result indicates that the dynamics of (3R)-β-tyrosine accumulation is different from those of other amino acids.

Academic Significance and Societal Importance of the Research Achievements

日本晴(イネ、ジャポニカ種)は非タンパク性アミノ酸(3R)-β-tyrosineを産生する.(3R)-β-Tyrosinは双子葉植物の根の伸長を特異的に阻害するが,イネ等の単子葉類には活性を示さない.(3R)-β-tyrosineおよびその類縁体を用いて構造と活性を比較したところ,活性発現にはβ-位のアミノ基とベンゼン環中のp-位の水酸基の共存が必要であった.イネには無害で,双子葉雑草に効果を示す薬剤のシーズ開発につながる成果を得た.

Report

(5 results)
  • 2020 Annual Research Report   Final Research Report ( PDF )
  • 2019 Research-status Report
  • 2018 Research-status Report
  • 2017 Research-status Report
  • Research Products

    (29 results)

All 2021 2019 2018 2017 Other

All Int'l Joint Research (3 results) Journal Article (6 results) (of which Int'l Joint Research: 3 results,  Peer Reviewed: 6 results,  Open Access: 2 results) Presentation (14 results) (of which Int'l Joint Research: 8 results,  Invited: 1 results) Book (2 results) Remarks (4 results)

  • [Int'l Joint Research] University of California at San Diego(米国)

    • Related Report
      2020 Annual Research Report
  • [Int'l Joint Research] University of California at San Diego(米国)

    • Related Report
      2018 Research-status Report
  • [Int'l Joint Research] University of California at San Diego(米国)

    • Related Report
      2017 Research-status Report
  • [Journal Article] イネ(日本晴)における(3R)-β-チロシン の生合成2021

    • Author(s)
      森直樹,阪本駿太,網干貴子,吉川貴徳,寺石政義,吉永直子,奥本裕
    • Journal Title

      生化学

      Volume: -

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Recent advances of chemical ecology: complex interactions medeated by molecules2021

    • Author(s)
      Mori N, Noge K
    • Journal Title

      Bioscience, Biotechnology, and Biochemistry

      Volume: 85 Issue: 1 Pages: 33-41

    • DOI

      10.1093/bbb/zbaa034

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Molecular basis of wax-based color change and UV reflection in dragonflies2019

    • Author(s)
      Futahashi, R., Yamahama, Y., Kawaguchi, M., Mori, N., Ishii, D., Okude, G., Hirai, Y., Kawahara-Miki, R., Yoshitake, K., Yajima, S., Hariyama, T., Fukatsu, T.
    • Journal Title

      eLife

      Volume: 8 Pages: 1-24

    • DOI

      10.7554/elife.43045

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Fragmentation study of isoflavones by IT-TOF-MS using biosynthesized isotopes2018

    • Author(s)
      Nakata, R., Yoshinaga, N., Teraishi, M., Okumoto, Y., Haffaker A., Schmelz, E.A., Mori, N.
    • Journal Title

      Biosci., Biotechnol. Biochem.

      Volume: 82 Issue: 8 Pages: 1309-1315

    • DOI

      10.1080/09168451.2018.1465810

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] A fragmentation study of isoflavones by IT-TOF-MS using biosynthesized isotopes2018

    • Author(s)
      Nakata R, Yoshinaga N, Teraishi M, Okumoto Y, Huffaker A, Schmelz EA, Mori N
    • Journal Title

      Bioscience, Biotechnology, and Biochemistry

      Volume: -

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Biosynthetic pathway of aliphatic formates via a Baeyer-Villiger oxidation in mechanism present in astigmatid mites.2017

    • Author(s)
      Shimizu N, Sakata D, Schmelz EA, Mori N, Kuwahara Y.
    • Journal Title

      Proc Natl Acad Sci U S A.

      Volume: 114 Issue: 10 Pages: 2616-2621

    • DOI

      10.1073/pnas.1612611114

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Presentation] イネがもつ(R)-β-tyrosine量の時間的変動2021

    • Author(s)
      阪本駿太,吉川貴徳,寺石政義,吉永直子,小野肇,森直樹
    • Organizer
      日本農芸化学会大会2021年度大会
    • Related Report
      2020 Annual Research Report
  • [Presentation] (R)-β-tyrosine がシロイヌナズナ根の細胞壁形成酵素に与える影響2019

    • Author(s)
      阪本駿太,井上貴斗,吉永直子,小林優,寺石政義,奥本裕,森直樹
    • Organizer
      日本農芸化学会2020年度大会
    • Related Report
      2019 Research-status Report
  • [Presentation] Unexpected origins of defensive compounds in animals2019

    • Author(s)
      Naoki Mori and Akira Mori
    • Organizer
      The 10 th Conference of Asia-Pacific Association of Chemical Ecologists
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] イネが生産する(R)-beta-tyrosineのシロイヌナズナにおける根の生育阻害活性2018

    • Author(s)
      中道雅貴、中田隆、吉永直子、小林優、寺石正義、奥本裕、森直樹
    • Organizer
      日本農芸化学会
    • Related Report
      2017 Research-status Report
  • [Presentation] イネに対する酢酸処理による乾燥耐性付与に伴う代謝変化2018

    • Author(s)
      伊左治俊作、吉永直子、土生芳樹、森直樹
    • Organizer
      日本農芸化学会
    • Related Report
      2017 Research-status Report
  • [Presentation] ビール酵母由来の多糖によるイネの根張り向上効果とイオン吸収能の変化2018

    • Author(s)
      持田真歩、中道貴也、森田智也、吉永直子、落合久美子、小林優、奥本裕、寺石政義、森直樹
    • Organizer
      日本農芸化学会
    • Related Report
      2017 Research-status Report
  • [Presentation] 画像解析を用いたダイズのハスモンヨトウ食害抵抗性因子の探索2018

    • Author(s)
      中田隆、手嶋伸、吉永直子、寺石政義、Eric Schmelz、奥本裕、森直樹
    • Organizer
      日本農芸化学会
    • Related Report
      2017 Research-status Report
  • [Presentation] Insights into rice (Oryza sativa L.) root growth promotion mediated by beta-1,3/1,6-glucans present in yeast cell wall2017

    • Author(s)
      Nakamichi T, Morita T, Yopshinaga N, Takasaki T, KItagawa T, Kobayashi M, Teraishi M, OkumotoY, Huffaker A, Schmela EA, Mori N
    • Organizer
      International Society of Chemical Ecology
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Metabolic changes in Oryza sativa accompanying acquisition of drought tolerance by acetic acid treatment2017

    • Author(s)
      Isaji S, Yoshinaga N, Habu Y, Mori N
    • Organizer
      International Society of Chemical Ecology
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Asian soybean rust-induced metabolites in a resistant soybean cultivar Hougyoku (PI 224270): structure determination and antifungal activity evaluation2017

    • Author(s)
      Nakata R, Tteishi H, Eizuka T, Yoshinaga N, Yeraishi M, OkumotoY, Huffaker A, Schmelz EA, N\Mori N
    • Organizer
      International Society of Chemical Ecology
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] The chemical analysis of bufadienolides in defensive glands of the Asian Rhabdophis sanakes2017

    • Author(s)
      Yoshida T, Jono T, Tkeuchi H, Ujiie R, Yoshinaga N, Ding L, Tang Y, Mori A, Mori N
    • Organizer
      International Society of Chemical Ecology
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Chemical analysis of bufadienolides in Japanese Lampyrine fireflies2017

    • Author(s)
      Ujiie R, Yoshida T, Takeuchi H, Eto T, Jono T, Yopshinaga N, Mori A, Mori N
    • Organizer
      International Society of Chemical Ecology
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Identification and investigation of compounds induced in apples by insect attack2017

    • Author(s)
      Tetsumoto Y, Yoshinaga N, Ishiguri Y, Mori N
    • Organizer
      International Society of Chemical Ecology
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Effect of inhibitory substances contained in calcium carbonate wettable powder on oviposition of peach fruit moth, Carposina sasakii (Lepidoptera: Carposinidae)2017

    • Author(s)
      Kazama H, Takanashi T, Tokoro M, Ishiguri Y, Mori N, YoshinagaN
    • Organizer
      International Society of Chemical Ecology
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Book] 蟲瞰学:持続可能な農業を創生するバイオミメティクスにおける農学・自然史学・工学連携 バイオミメティクス・エコノミクス(下村政嗣監修)2021

    • Author(s)
      森直樹
    • Total Pages
      367
    • Publisher
      シーエムシー出版社
    • ISBN
      9784781315638
    • Related Report
      2020 Annual Research Report
  • [Book] Chemical Ecology of Insects, Applications and Associations with Plants and Microbes2018

    • Author(s)
      Yoshinaga N, Mori N (edited by Tabata J)
    • Total Pages
      296
    • Publisher
      CRC Press, Taylor & Francis Group
    • Related Report
      2017 Research-status Report
  • [Remarks] http://www.chemeco.kais.kyoto-u.ac.jp/

    • Related Report
      2020 Annual Research Report
  • [Remarks] 京都大学農学研究科応用生命科学専攻化学生態学分野HP

    • URL

      http://www.chemeco.kais.kyoto-u.ac.jp/publications.html

    • Related Report
      2019 Research-status Report
  • [Remarks]

    • URL

      http://www.chemeco.kais.kyoto-u.ac.jp/

    • Related Report
      2018 Research-status Report
  • [Remarks] 京都大学農学研究科応用生命科学専攻化学生態学分野

    • URL

      http://www.chemeco.kais.kyoto-u.ac.jp/

    • Related Report
      2017 Research-status Report

URL: 

Published: 2017-04-28   Modified: 2022-02-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi