| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2019: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2018: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2017: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Outline of Final Research Achievements |
Relationships between immune parameters and the environmental factors were examined in the cecum of rats fed the diet containing fructooligosaccharides. Mucosal inflammation was involved in the IgA secretion promoting effect observed in the early stage ofingestion of the semi-purified diet containing fructooligosaccharides, and the mucin layer was disrupted in the cecum. On the other hand, these series of responses were all canceled during long-term intake and non-purified feed intake. In addition, a series of responses was considered to be induced by changes in the intestinal environment such as the accumulation of lactic acid and the accompanying drastic pH decrease.
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