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Reduction of mercury levels in cultured fish and development of human supplements using the inhibitory effect of vegetables on mercury absorption

Research Project

Project/Area Number 17K07948
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Aquatic life science
Research InstitutionKindai University

Principal Investigator

Masashi Ando  近畿大学, 農学部, 教授 (80247965)

Project Period (FY) 2017-04-01 – 2021-03-31
Project Status Completed (Fiscal Year 2020)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2020: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2019: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2018: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2017: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Keywordsメチル水銀 / 野菜 / 養殖魚 / デトックス / 腸 / 腸管 / Caco2細胞 / 水銀 / サプリメント
Outline of Final Research Achievements

Throughout the study, although it was only at the level of model experiments, it was recognized that there may be many kinds of substances with different molecular weights and electrical properties that have an inhibitory effect on mercury absorption in various vegetables. It is unfortunate that the final results did not show efficacy in breeding experiments. However, if we can isolate the substances and increase the rate of incorporation into the diet, it is highly expected to reduce the mercury level in fish. Various improvements have been made to the evaluation system for the isolation of the substance, and the fact that a foundation for further research with higher precision has been established is also a major achievement of this study.

Academic Significance and Societal Importance of the Research Achievements

メチル水銀の吸収は特に胎児にとって問題となる。これを軽減するため野菜汁の有効性を検討してきたが,多くの野菜がメチル水銀の吸収をある程度抑えられることが明らかとなった。これが養殖魚の餌に混入されることで,魚自身の水銀濃度を下げることができ,将来的にはヒト向けのデトックスサプリメントの材料になることが期待できる。

Report

(5 results)
  • 2020 Annual Research Report   Final Research Report ( PDF )
  • 2019 Research-status Report
  • 2018 Research-status Report
  • 2017 Research-status Report
  • Research Products

    (7 results)

All 2021 2020 2019 2018

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results) Presentation (6 results)

  • [Journal Article] Evaluation of the inhibition of mercury absorption by vegetable juices using a red sea bream intestine model2020

    • Author(s)
      Masashi Ando, Takahiro Yamada, Yoichiro Okinaga, Etsuko Taguchi, You Sugimoto,Akiko Takeuchi, Tomohiro Itoh, Takashi Fukuda, Yasuyuki Tsukamasa
    • Journal Title

      Food Chemistry

      Volume: 303 Pages: 12535-12535

    • DOI

      10.1016/j.foodchem.2019.125351

    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] 完全養殖クロマグロの水銀に関する研究-XIII -メチル水銀吸収阻害効果を有するゴボウ成分の探索-2021

    • Author(s)
      安藤正史,中山貴生,數山裕人,眞野彰太,福田隆志,塚正泰之
    • Organizer
      令和3年度日本水産学会春季大会
    • Related Report
      2020 Annual Research Report
  • [Presentation] 完全養殖クロマグロの水銀に関する研究-XIII -メチル水銀吸収阻害効果を有するゴボウ成分の探索-2020

    • Author(s)
      安藤正史・中山貴生・數山裕人・眞野彰太 福田隆志・塚正泰之
    • Organizer
      令和2年度度日本水産学会春季大会
    • Related Report
      2019 Research-status Report
  • [Presentation] Caco-2細胞モデルによる野菜汁からの水銀吸収阻害物質の探索2019

    • Author(s)
      安藤正史
    • Organizer
      メチル水銀研究ミーティング
    • Related Report
      2019 Research-status Report
  • [Presentation] 完全養殖クロマグロの水銀に関する研究-12 -ゴボウ成分のメチル水銀吸収阻害効果に及ぼす影響-2019

    • Author(s)
      安藤正史・朴 世朱・箱谷一樹・福田隆志・塚正泰之
    • Organizer
      平成31年度日本水産学会春季大会
    • Related Report
      2018 Research-status Report
  • [Presentation] 野菜類からのメチル水銀吸収抑制物質の探索2018

    • Author(s)
      安藤正史
    • Organizer
      メチル水銀研究ミーティング
    • Related Report
      2018 Research-status Report
  • [Presentation] 野菜成分のメチル水銀吸収阻害効果に及ぼす凍結操作の影響2018

    • Author(s)
      安藤正史・福田隆志・塚正泰之
    • Organizer
      平成30年度日本水産学会春季大会
    • Related Report
      2017 Research-status Report

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Published: 2017-04-28   Modified: 2022-01-27  

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