| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2019: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2018: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2017: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Outline of Final Research Achievements |
The analysis of the artificial regulation of chicken embryo development was carried out with a focus on heat shock protein 90 (HSP90). Both HSP90 mRNA and protein were expressed in throughout the embryo suggested that HSP90 was be involved in the regulation of development throughout the embryo. Furthermore, we found that HSP90 was able to regulate the cell cycle in the primary cultured chick embryos hepatocytes. However, the results of in ovo administration of HSP90 and HSP90 inhibitors shown that regulation of embryonic development by HSP90 and factors interacting with HSP90 should be investigated.
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