Association between Polymorphisms of Temperament Related Genes and Behavioral Traits in Japanese Black Cattle.

• Project/Area Number: 17K08064
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Animal production science
• Research Institution: Hiroshima University
• Principal Investigator: BUNGO TAKASHI 広島大学, 統合生命科学研究科(生), 教授 (40325361)
• Project Period (FY): 2017-04-01 – 2020-03-31
• Project Status: Completed (Fiscal Year 2019)
• Budget Amount: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000); Fiscal Year 2019: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2018: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2017: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
• Keywords: 気質 / 遺伝子多型 / 行動特性 / 肉牛 / 扱いやすさ

Outline of Final Research Achievements

(1) Play behavior in Japanese Black calves gradually declines as they mature and that it may be controlled by variations in the MAOA gene. (2) Facial hair whorl location may be effective to predict temperament in cattle, but that there are some temperaments to change under the influence of environment and/or handlings. (3) By analyzing the association between the polymorphisms and temperament scores of behavioral tests, significant effects of CRH polymorphism and interaction were not detected but cattle with wild homo-type of LEP tended to permit the contact of stranger when feeding (4) SNPs (calpastin, Leptin and acylCoA- diacylglycerol-acyltransferase) affect temperament in Japanese Black cattle. (5) Thermotolerance scores, cattle without the wild-type allele of UCP and NPY showed low scores of thermotolerance and disease resistance.

Academic Significance and Societal Importance of the Research Achievements

本試験で構築した質問調査票および行動試験が気質評価に有効で、気質を指標とした選抜において参考となると考えられた。気質と遺伝子変異との関係はあるものの、飼育管理によって扱いやすさは改善できる可能性も考えられ、遺伝型を考慮した上で群管理行うことも必要であろう。これらの知見は今後の育種選抜の参考になること、生産現場において日頃の家畜との接し方を再考する契機になるものと期待される。

Research Products

• [Journal Article] Association between temperament and polymorphisms of CRH and leptin in Japanese Black cattle. (2020)
  • Author(s): Aierqing, S., Nakagawa, A., and Bungo, T.
  • Journal Title: Journal of Advanced Veterinary and Animal Research Volume: 7 Issue: 1 Pages: 1-5
  • DOI: 10.5455/javar.2020.g386
  • Peer Reviewed / Open Access
• [Journal Article] Sex, age or genetic differences related to play behaviors in Japanese Black calves. (2019)
  • Author(s): Aierqing, S., Nakagawa, A., Okita, M. and Bungo, T.
  • Journal Title: Animal Science Journal Volume: 90 Issue: 10 Pages: 1407-1413
  • DOI: 10.1111/asj.13283
  • Peer Reviewed
• [Presentation] Polymorphisms in the energy metabolism related genes are associated with thermotolerance and disease resistance in dairy cows. (2019)
  • Author(s): Bungo, T., Amimoto, M., Aierquing, S. and Okita, M.
  • Organizer: The 2nd International Conference on Tropical Animal Science and Production
  • Int'l Joint Research
• [Presentation] 黒毛和種肥育牛の気質と代謝関連遺伝子多型との関係． (2019)
  • Author(s): エルチンサレンゴウワ・大内義光・沖田美紀・豊後貴嗣
  • Organizer: 動物の行動と管理学会．
• [Presentation] Association between Temperament and Polymorphisms of CRH and Leptin in Japanese Black Cattle. (2018)
  • Author(s): Aierqing, S., Nakagawa, A., Okita, M. and Bungo, T.
  • Organizer: The 18th AAAP Animal Production Congress．
  • Int'l Joint Research
• [Presentation] 新疆ウイグル自治区におけるウシの気質調査 (2018)
  • Author(s): エルチンサレンゴウワ・中川明子・豊後貴嗣
  • Organizer: 日本家畜管理学会