| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2019: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2018: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Outline of Final Research Achievements |
It has been reported that protein ubiquitination plays an important role for regulation of biological functions. However, it is difficult to analyze protein ubiquitination in cell. In this study, we attempted to identify artificial ubiquitin compounds for development of the method to detect and to quantify cellular levels of protein ubiquitination. As a result, we identified compounds recognized as substrates by ubiquitin activating enzyme like a ubiquitin molecule.
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