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Elucidation of the mechanism of dispensing error based on the behavioral psychology of pharmacists and application to clinical practice

Research Project

Project/Area Number 17K08447
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Medical pharmacy
Research InstitutionKyushu University

Principal Investigator

Tsuji Toshikazu  九州大学, 大学病院, 副薬剤部長 (80791748)

Project Period (FY) 2017-04-01 – 2021-03-31
Project Status Completed (Fiscal Year 2020)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2019: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2018: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords調剤エラー / アイトラッキング / 視線動向 / エラーメカニズム / 薬剤師 / 発生タイミング / 発生場所 / 患者への危険性 / 医療薬学教育学 / リスクマネジメント
Outline of Final Research Achievements

In this study, we measured the gaze movement of the pharmacists by using the eye-tracking method. As a result, we could elucidate the confirmation procedure in dispensing and the causes of dispensing errors from the viewpoint of recognition and behavior of pharmacists. Also, we revealed that drugs with double specifications are safe by their right-slanted placement, and could show that the complication of dispensing is related to “single specification drug < double specification drug, left-side area < right-side area.” Furthermore, we were able to identify one of the behaviors of pharmacists that the confirmation procedure in dispensing was changed in the right-side area due to the difficulty to identify the drug location. Based on the new findings obtained in this study, we can reduce dispensing errors by pharmacists, thereby further improving the quality and safety of medical care.

Academic Significance and Societal Importance of the Research Achievements

これまで多くの医療機関で調剤エラーやインシデント防止向けた様々な取り組みがなされてきたが、どのような薬剤がどのような配置(環境)にある時にエラーが発生しやすいのかを明らかにした報告はなかった。本研究では、アイトラッキング手法を応用して薬剤師の調剤時の視線動向を検証することで、エラーを誘発しやすい調剤環境の要因、薬剤師の記憶容量の限界に伴う行動心理の1つを明らかにすることができた。
なお、本研究成果である「アイトラッキング手法を用いた薬剤師の視線動向に基づく調剤エラーの発生メカニズムの解明(医療薬学誌)」の論文は、2020年度の医療薬学誌論文賞を受賞しており、学術的・社会的に評価されている。

Report

(5 results)
  • 2020 Annual Research Report   Final Research Report ( PDF )
  • 2019 Research-status Report
  • 2018 Research-status Report
  • 2017 Research-status Report
  • Research Products

    (12 results)

All 2021 2020 2019 2018

All Journal Article (7 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 7 results,  Open Access: 2 results) Presentation (5 results)

  • [Journal Article] Continuous monitoringof neutrophils to lymphocytes ratio for estimating the onset, severity, and subsequent prognosis of immune related adverse events2021

    • Author(s)
      Ryosuke Matsukane, Hiroyuki Watanabe, Haruna Minami, Kojiro Hata, Kimitaka Suetsugu, Toshikazu Tsuji, Satohiro Masuda, Isamu Okamoto, Takashi Nakagawa, Takamichi Ito, Masatoshi Eto, Masaki Mori, Yoichi Nakanishi, Nobuaki Egashira
    • Journal Title

      Sci Rep

      Volume: 11(1), 1324 Issue: 1 Pages: 1324-1324

    • DOI

      10.1038/s41598-020-79397-6

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] 職業性曝露防止に着目した廃棄容器からの抗がん薬汚染状況調査2021

    • Author(s)
      橋本昂介,入佐俊弘,石田茂,秦 晃二郎,中嶋一惠,渡邊裕之,辻敏和,江頭伸昭,家入一郎
    • Journal Title

      医療薬学

      Volume: 47(4) Pages: 200-207

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Increasing Diluent Volume Decreases Bendamustine-induced Venous Irritation without Reducing the Therapeutic Efficacy2020

    • Author(s)
      Shigeru Ishida, Hanae Morikawa, Hiroyuki Watanabe, Takeshi Sugio, Yasuo Mori, Toshikazu Tsuji, Satohiro Masuda, Toshihiro Miyamoto, Koichi Akashi, Nobuaki Egashira
    • Journal Title

      Biol. Pharm. Bull

      Volume: 43(3) Pages: 488-492

    • NAID

      130007804434

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of diluent volume and administration time on the incidence of anaphylaxis following docetaxel therapy in breast cancer2020

    • Author(s)
      Shigeru Ishida, Ken Masuguchi, Takehiro Kawashiri, Shintaro Matsumoto, Mio Fukuda, Yuko Yoshizawa, Haruna Minami, Takafumi Nakashima, Mami Saito, Kojiro Hata, Toshikazu Tsuji, Akiko Kanaya, Hiroyuki Watanabe, Satohiro Masuda, Nobuaki Egashira
    • Journal Title

      Biol. Pharm. Bull

      Volume: 43(4) Pages: 663-668

    • NAID

      130007825263

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Usefulness of daily folic acid supplementation during methotrexate treatment of Japanese patients with rheumatoid arthritis2020

    • Author(s)
      Keiichi Sasaki, Toshikazu Tsuji (corresponding author), Yasutaka Kimoto, Yuki Yanagihara, Ken Masuguchi, Ayako Chikamori, Hiroyuki Watanabe, Tesshin Murakami, Daisuke Oryoji, Masafumi Hashimoto, Takahiko Horiuchi, Nobuaki Egashira
    • Journal Title

      Modern Rheumatology

      Volume: 31(1) Issue: 1 Pages: 108-113

    • DOI

      10.1080/14397595.2020.1743493

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Risk Factors for Gemcitabine-Induced Vascular Pain in Patients With Pancreatic Cancer2020

    • Author(s)
      Shigeru Ishida, Yoko Makihara, Hiroyuki Watanabe, Takafumi Nakashima, Kenichiro Nagata, Kimitaka Suetsugu, Toshikazu Tsuji, Kojiro Hata, Munehiko Ikeda, Mio Ikebe, Haruna Minami, Hitomi Watanabe, Kohei Nakata, Masafumi Nakamura, Nobuaki Egashira, Ichiro Ieiri
    • Journal Title

      The Annals of Pharmacotherapy

      Volume: -

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] アイトラッキング手法を用いた薬剤師の視線動向に基づく調剤エラーの発生メカニズムの解明2019

    • Author(s)
      辻敏和, 永田健一郎, 佐々木恵一, 末次王卓, 渡邊裕之, 金谷朗子, 増田智先
    • Journal Title

      医療薬学

      Volume: 39(9) Pages: 493-503

    • NAID

      130007898999

    • Related Report
      2019 Research-status Report
    • Peer Reviewed
  • [Presentation] 機械学習を用いた 医薬品の過量・過少オーダの検出2020

    • Author(s)
      永田 健一郎,辻 敏和,村岡 香代子,渡邊 裕之,金谷 朗子,江頭 伸昭,家入 一郎
    • Organizer
      第30回日本医療薬学会年会(オンライン学会,口頭発表),名古屋
    • Related Report
      2020 Annual Research Report
  • [Presentation] 腎機能の低下したAIDS患者に対する初回治療としてのドルテグラビル+ラミブジン2剤療法における薬学的管理の1例2020

    • Author(s)
      松本慎太郎,石田茂,渡邊裕之,辻敏和,松本佑慈,江頭伸昭,家入一郎
    • Organizer
      第30回日本医療薬学会年会(オンライン学会,ポスター発表),名古屋
    • Related Report
      2020 Annual Research Report
  • [Presentation] 肺がん患者のがん薬物療法における腎障害を反映する尿中バイオマーカーの探索2020

    • Author(s)
      田島壮一郎,渡邊裕之,福田未音,田川慎二,佐田裕子,槇原洋子,秦晃二郎,辻敏和,岡本勇,増田智先,江頭伸昭,家入一郎
    • Organizer
      第30回日本医療薬学会年会(オンライン学会,口頭発表),名古屋
    • Related Report
      2020 Annual Research Report
  • [Presentation] アイトラッキング手法を用いた薬剤師の視線動向に基づく調剤エラーの発生メカニズムの解明2019

    • Author(s)
      辻敏和, 永田健一郎, 佐々木恵一, 末次王卓, 渡邊裕之, 金谷朗子, 増田智先
    • Organizer
      第29回日本医療薬学会年会
    • Related Report
      2019 Research-status Report
  • [Presentation] 調剤エラーの発生メカニズムと患者への危険性との関係2018

    • Author(s)
      辻敏和
    • Organizer
      日本薬学会第138回年会
    • Related Report
      2017 Research-status Report

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Published: 2017-04-28   Modified: 2022-01-27  

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