Evaluation of cubic-phase drug-carrier nanoparticles
Project/Area Number |
17K08467
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Medical pharmacy
|
Research Institution | Toho University |
Principal Investigator |
|
Co-Investigator(Kenkyū-buntansha) |
伊藤 雅隆 東邦大学, 薬学部, 助教 (30792410)
|
Project Period (FY) |
2017-04-01 – 2020-03-31
|
Project Status |
Completed (Fiscal Year 2019)
|
Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2019: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2018: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2017: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
|
Keywords | X線吸収スペクトル法 / X線吸収端近傍構造 / X線吸収スペクトル測定法 / 薬物担体 / 物性評価 / 難溶性薬物の可溶化 / 新規薬物担体 |
Outline of Final Research Achievements |
X-ray absorption near-edge structure (XANES) spectroscopy was applied to evaluate the active pharmaceutical ingredients for the first time. The method could reveal the chemical environment of the X-ray absorbing atoms, indicating that the method would be a potent method for evaluating the APIs in pharmaceutics including cubic-phase nanoparticles.
|
Academic Significance and Societal Importance of the Research Achievements |
X線吸収端近傍構造(XANES)測定法は、固形製剤から液状製剤まで、様々な形態の製剤中の医薬品原薬の分析が可能であり、医薬品製剤のより精密な評価に適用できると期待できる。
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Report
(4 results)
Research Products
(12 results)