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Lifestyle change and its impact on future savings in direct medical costs

Research Project

Project/Area Number 17K08903
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Medical sociology
Research InstitutionNational Cancer Center Japan

Principal Investigator

Saito Eiko  国立研究開発法人国立がん研究センター, がん対策情報センター, 研究員 (60738079)

Project Period (FY) 2017-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2019: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2018: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2017: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords医療費 / がん / マイクロシミュレーション / 禁煙治療 / 医療経済 / 医療経済学 / がん疫学 / 医療 / 社会医学 / 生活習慣
Outline of Final Research Achievements

This research aims to assess the future cost savings in medical costs induced by lifestyle changes. During the study period, we have achieved the followings: 1) using the microsimulation modelling methods, costs and cost-effectiveness of endoscopy screening were performed, which incorporated smoking status and birth cohorts. 2) We assessed the impact of perioperative smoking cessation treatment on subsequent medical costs. Our results showed that smoking cessation after surgery may reduce the medical costs if continued properly.

Academic Significance and Societal Importance of the Research Achievements

本研究から、禁煙は肺がん患者において術後医療費の抑制につながることが明らかとなった。また、頑健性の高い自然史モデルと介入モデルを組み合わせたマイクロシミュレーションの手法を用いて定期的内視鏡検診の経済効果を検討した結果、適切な開始年齢と受診間隔での上部消化管内視鏡検査受診によって、生命年が延伸されるだけでなく、費用対効果も向上することが明らかになった。本研究から、検診受診と生活習慣改善は健康の向上に資するのみならず、医療費抑制にもつながる可能性が示唆された。

Report

(4 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Research-status Report
  • 2017 Research-status Report
  • Research Products

    (19 results)

All 2021 2020 2019 2018 2017 Other

All Int'l Joint Research (1 results) Journal Article (11 results) (of which Int'l Joint Research: 3 results,  Peer Reviewed: 11 results,  Open Access: 8 results) Presentation (6 results) (of which Int'l Joint Research: 4 results,  Invited: 2 results) Book (1 results)

  • [Int'l Joint Research] コロンビア大学/ハーバードメディカルスクール(米国)

    • Related Report
      2018 Research-status Report
  • [Journal Article] The Association Between Habitual Sleep Duration and Mortality According to Sex and Age: The Japan Public Health Center-based Prospective Study2021

    • Author(s)
      Svensson T, Inoue M, Saito E, Sawada N, Iso H, Mizoue T, Goto A, Yamaji T, Shimazu T, Iwasaki M, Tsugane S.
    • Journal Title

      Journal of Epidemiology

      Volume: 31 Issue: 2 Pages: 109-118

    • DOI

      10.2188/jea.JE20190210

    • NAID

      130007981112

    • ISSN
      0917-5040, 1349-9092
    • Year and Date
      2021-02-05
    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Cancer incidence attributable to tuberculosis in 2015: Global, regional, and national estimates2020

    • Author(s)
      Leung Chi Yan、Huang Hsi-Lan、Rahman Md. Mizanur、Nomura Shuhei、Krull Abe Sarah、Saito Eiko、Shibuya Kenji
    • Journal Title

      BMC Cancer

      Volume: 20 Issue: 1

    • DOI

      10.1186/s12885-020-06891-5

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Long-term Trends in Prostate Cancer Incidence by Stage at Diagnosis in Japan Using the Multiple Imputation Approach, 1993-20142020

    • Author(s)
      Saito Eiko、Hori Megumi、Matsuda Tomohiro、Yoneoka Daisuke、Ito Yuri、Katanoda Kota
    • Journal Title

      Cancer Epidemiology Biomarkers & Prevention

      Volume: 19 Issue: 6 Pages: 1228-1228

    • DOI

      10.1158/1055-9965.epi-19-1228

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] JPHC Study Group. Impact of alcohol drinking on cancer risk with consideration of flushing response: The Japan Public Health Center-based Prospective Study Cohort (JPHC study)2020

    • Author(s)
      Ono A, Inoue M, Sawada N, Saito E, Yamaji T, Shimazu T, Goto A, Iwasaki M, Tsugane S
    • Journal Title

      Prev Med.

      Volume: 133 Pages: 106026-106026

    • DOI

      10.1016/j.ypmed.2020.106026

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Prevalence of diabetes in Japanese patients with cancer2020

    • Author(s)
      Saito Eiko、Goto Atsushi、Kanehara Rieko、Ohashi Ken、Noda Mitsuhiko、Matsuda Tomohiro、Katanoda Kota
    • Journal Title

      Journal of Diabetes Investigation

      Volume: - Issue: 5 Pages: 1159-1162

    • DOI

      10.1111/jdi.13231

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Effect of body-mass index on the risk of gastric cancer: A population-based cohort study in A Japanese population2019

    • Author(s)
      Hirabayashi Mayo、Inoue Manami、Sawada Norie、Saito Eiko、Abe Sarah K.、Hidaka Akihisa、Iwasaki Motoki、Yamaji Taiki、Shimazu Taichi、Shibuya Kenji、Tsugane Shoichiro
    • Journal Title

      Cancer Epidemiology

      Volume: 63 Pages: 101622-101622

    • DOI

      10.1016/j.canep.2019.101622

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Helicobacter pylori infection, atrophic gastritis, and risk of pancreatic cancer: A population-based cohort study in a large Japanese population: the JPHC Study2019

    • Author(s)
      Hirabayashi Mayo、Inoue Manami、Sawada Norie、Saito Eiko、Abe Sarah K.、Hidaka Akihisa、Iwasaki Motoki、Yamaji Taiki、Shimazu Taichi、Tsugane Shoichiro
    • Journal Title

      Scientific Reports

      Volume: 9 Issue: 1

    • DOI

      10.1038/s41598-019-42365-w

    • Related Report
      2019 Annual Research Report 2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Association of Diabetes With All-Cause and Cause-Specific Mortality in Asia: A Pooled Analysis of More Than 1 Million Participants2018

    • Author(s)
      Yang JJ, Yu D, Wen W, Saito E, Rahman S, Shu XO, et al.
    • Journal Title

      JAMA Netw Open

      Volume: 2(4) Issue: 4 Pages: e192696-e192696

    • DOI

      10.1001/jamanetworkopen.2019.2696

    • Related Report
      2019 Annual Research Report 2018 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Tobacco Smoking and Mortality in Asia: A Pooled Meta-analysis2018

    • Author(s)
      Yang JJ, Yu D, Wen W, Shu XO, Saito E, Rahman S, et al.
    • Journal Title

      JAMA Netw Open

      Volume: 2(3) Issue: 3 Pages: e191474-e191474

    • DOI

      10.1001/jamanetworkopen.2019.1474

    • Related Report
      2019 Annual Research Report 2018 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Impact of Alcohol Intake and Drinking Patterns on Mortality From All Causes and Major Causes of Death in a Japanese Population2018

    • Author(s)
      Saito E, Inoue M, Sawada N, Charvat H, Shimazu T, Yamaji T, Iwasaki M, Sasazuki S, Mizoue T, Iso H, Tsugane S.
    • Journal Title

      Journal of Epidemiology

      Volume: 28 Issue: 3 Pages: 140-148

    • DOI

      10.2188/jea.JE20160200

    • NAID

      130006434064

    • ISSN
      0917-5040, 1349-9092
    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Smoking cessation and subsequent risk of cancer: A pooled analysis of eight population-based cohort studies in Japan2017

    • Author(s)
      Saito E, Inoue M, Tsugane S, Ito H, Matsuo K, Wakai K, Wada K, Nagata C, Tamakoshi A, Sugawara Y, Tsuji I, Mizoue T, Tanaka K, Sasazuki S
    • Journal Title

      Cancer Epidemiol

      Volume: Dec;51 Pages: 98-108

    • DOI

      10.1016/j.canep.2017.10.013

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Presentation] Long-term trends in prostate cancer incidence by stage at diagnosis in Japan using multiple imputation approach, 1993-20142019

    • Author(s)
      Saito E, Hori M, Matsuda T, Yoneoka D, Ito Y, Katanoda K
    • Organizer
      Preventing Overdiagnosis 2019
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Trends in esophageal cancer incidence in Japan2019

    • Author(s)
      Saito E
    • Organizer
      Cancer Intervention and Surveillance Modelling Network (CISNET) 2019 Mid-Year Meeting
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Epidemiology of esophageal cancer in Japan2018

    • Author(s)
      Saito E
    • Organizer
      The Cancer Intervention and Surveillance Modelling Network (CISNET) 2018 Annual Meeting
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Benefits and harms of gastric cancer screening and prevention in Japan: A microsimulation modeling analysis2018

    • Author(s)
      Leung CY, Huang HL, Saito E et al.
    • Organizer
      The 25th World Cancer Congress
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research
  • [Presentation] Smoking cessation and subsequent risk of cancer: A pooled analysis of eight population-based cohort studies in Japan2018

    • Author(s)
      齋藤英子
    • Organizer
      日本癌学会
    • Related Report
      2018 Research-status Report
  • [Presentation] Benefits, burden, and harms of gastric cancer screening and prevention in Japan: a microsimulation model to quantify intervention options using cancer registry data2018

    • Author(s)
      齋藤英子
    • Organizer
      ASEANがん登録フォーラム2018
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Book] 「第2章 医薬品市場・売上予測の手法と患者数予測の活用 第6節 がんの年齢階級別罹患数の将来予測」、医薬品マーケティングにおける市場・売上予測と戦略策定2019

    • Author(s)
      齋藤英子、片野田耕太
    • Total Pages
      538
    • Publisher
      技術情報協会
    • ISBN
      9784861047404
    • Related Report
      2018 Research-status Report

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Published: 2017-04-28   Modified: 2021-02-19  

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