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Application of behavioral economics in the analysis of the effects of socioeconomic status on the progression of chronic complications in patients with diabetes mellitus.

Research Project

Project/Area Number 17K08936
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Medical sociology
Research InstitutionNippon Medical School

Principal Investigator

Emoto Naoya  日本医科大学, 医学部, 教授 (50160388)

Co-Investigator(Kenkyū-buntansha) 小谷野 肇  順天堂大学, 医学部, 准教授 (80291897)
Project Period (FY) 2017-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2019: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2018: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords行動経済学 / リテラシー / socioeconomic status / 糖尿病 / 網膜症 / 学歴 / 糖尿病合併症 / 危険回避度 / 認知機能 / 2型糖尿病 / cognitive function
Outline of Final Research Achievements

Patient's risk preference is an important factor for the progression of diabetic complications. Patients who cannot understand the concept of probability because of lower literacy skills may act as if their preferences are risk loving. We hypothesized that diabetic patients with higher educational levels have higher literacy skills, act as risk avoiding, and have less diabetic complications. In the present study, we performed behavioral economics survey of patients with diabetes. We found that patients who had higher educational levels were inclined to give reasonable answers, but the effects of educational levels were abolished in patients complicated with retinopathy. Educational attainment seems to be the result of patients’ socioeconomic status in their childhood. Low literacy may be an independent risk factor for the progression of diabetic complications regardless of the socioeconomic status, although it is unknown whether it is a cause or a result of the disease.

Academic Significance and Societal Importance of the Research Achievements

糖尿病の治療では自覚症状がない段階から自分の未来の健康を害する要因を正しく理解して危険を回避する行動が重要である。それには与えられた情報を正しく理解する認知機能が必要である。一般に学歴が高いほど認知機能は高い。しかし、糖尿病で網膜症が進行している患者に限っては学歴と認知機能の相関が消失していた。糖尿病で合併症が進行する患者では、何らかの理由で認知機能が落ちている可能性があるが、それは必ずしも先天的に認知機能が低いことを意味しない。学歴や職業にかかわらず認知機能の低下が糖尿病合併症進行の危険因子であることを念頭に治療介入戦略を立案することによって、糖尿病合併症進行を抑制できると考えられる。

Report

(4 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Research-status Report
  • 2017 Research-status Report
  • Research Products

    (11 results)

All 2020 2019 2018 2017

All Journal Article (4 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 4 results,  Open Access: 1 results) Presentation (7 results) (of which Int'l Joint Research: 1 results)

  • [Journal Article] Association of vitamin D levels and vitamin D-related gene polymorphisms with liver fibrosis in patients with biopsy-proven nonalcoholic fatty liver disease.2019

    • Author(s)
      Arai T, Atsukawa M, Tsubota A, Koeda M, Yoshida Y, Okubo T, Nakagawa A, Itokawa N, Kondo C, Nakatsuka K, Masu T, Kato K, Shimada N, Hatori T, Emoto N, Kage M, Iwakiri K.
    • Journal Title

      Dig Liver Dis.

      Volume: in press Issue: 7 Pages: 1036-1042

    • DOI

      10.1016/j.dld.2018.12.022

    • Related Report
      2018 Research-status Report
    • Peer Reviewed
  • [Journal Article] Postprandial Hyperchylomicronemia and Thin-Cap Fibroatheroma in Nonculprit Lesions.2018

    • Author(s)
      Kurihara O, Okajima F, Takano M, Kato K, Munakata R, Murakami D, Miyauchi Y, Emoto N, Sugihara H, Seino Y, Shimizu W.
    • Journal Title

      Arterioscler Thromb Vasc Biol.

      Volume: 38 Issue: 8 Pages: 1940-1947

    • DOI

      10.1161/atvbaha.118.311245

    • Related Report
      2018 Research-status Report
    • Peer Reviewed
  • [Journal Article] Basal-Bolus Insulin Therapy with Gla-300 During Hospitalization Reduces Nocturnal Hypoglycemia in Patients with Type 2 Diabetes Mellitus: A Randomized Controlled Study.2018

    • Author(s)
      Okajima F, Nakamura Y, Yamaguchi Y, Shuto Y, Kato K, Sugihara H, Emoto N.
    • Journal Title

      Diabetes Ther.

      Volume: 9 Issue: 3 Pages: 1049-1059

    • DOI

      10.1007/s13300-018-0419-z

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Serum Wisteria floribunda agglutinin-positive Mac-2 binding protein more reliably distinguishes liver fibrosis stages in non-alcoholic fatty liver disease than serum Mac-2 binding protein2018

    • Author(s)
      Atsukawa Masanori、Tsubota Akihito、Okubo Tomomi、Arai Taeang、Nakagawa Ai、Itokawa Norio、Kondo Chisa、Kato Keizo、Hatori Tsutomu、Hano Hiroshi、Oikawa Tsunekazu、Emoto Naoya、Abe Masanori、Kage Masayoshi、Iwakiri Katsuhiko
    • Journal Title

      Hepatol Res

      Volume: in press Issue: 6 Pages: 424-432

    • DOI

      10.1111/hepr.13046

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Presentation] Socioeconomic Status, Literacy, and Sex Differences in the Progression of Retinopathy in Patients With Type 2 Diabetes in Tokyo, Japan.2020

    • Author(s)
      Naoya Emoto, Akimi Soga, Izumi Fukuda, Kyoko Tanimura-Inagaki, Taro Harada, Hitoshi Sugihara , Rei Goto,
    • Organizer
      Endocrine Society’s Annual Meeting, San Francisco, CA, United States. (Conference canceled)
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 糖尿病患者の危険回避度と合理的判断能力2019

    • Author(s)
      曽我彬美、江本直也、福田いずみ、稲垣恭子、原田太郎、杉原 仁、後藤励
    • Organizer
      第62回日本糖尿病学会年次学術集会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 行動経済学的手法による血糖コントロール不良患者の危険回避度分析2018

    • Author(s)
      曽我 彬美, 江本 直也, 福田 いずみ, 稲垣 恭子, 原田 太郎, 杉原 仁, 後藤 励
    • Organizer
      第61回日本糖尿病学会年次学術集会
    • Related Report
      2018 Research-status Report
  • [Presentation] 食事療法及び強化インスリン療法を用いた血糖コントロールが薬物治療歴のない2型糖尿病患者の血中グルカゴン濃度に与える影響2018

    • Author(s)
      岡島 史宜,,山口 祐司, 仲村 優子, 周東 佑樹, 杉原 仁, 江本 直也
    • Organizer
      第61回日本糖尿病学会年次学術集会
    • Related Report
      2018 Research-status Report
  • [Presentation] 糖尿病患者の危険回避度評価における質問票リテラシーの問題2018

    • Author(s)
      曽我彬美,江本直也,福田いずみ,稲垣恭子,原田太郎,杉原仁,後藤励
    • Organizer
      行動経済学会 第12回大会
    • Related Report
      2018 Research-status Report
  • [Presentation] 1型および2型糖尿病患者における社会経済状況が合併症進行へ及ぼす影響の比較検討.2017

    • Author(s)
      江本直也、岡島史宜、杉原仁、後藤励
    • Organizer
      第60回日本糖尿病学会年次学術集会
    • Related Report
      2017 Research-status Report
  • [Presentation] 治療困難な糖尿病患者の血糖コントロールに関与する行動経済学的要因分析2017

    • Author(s)
      江本直也
    • Organizer
      行動経済学会 第11回大会
    • Related Report
      2017 Research-status Report

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Published: 2017-04-28   Modified: 2021-02-19  

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