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Research on decision process for recomendation grade in clinical practice guidelines

Research Project

Project/Area Number 17K08941
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Medical sociology
Research InstitutionTeikyo University (2018-2019)
National Cancer Center Japan (2017)

Principal Investigator

Hamashima Chisato  帝京大学, 医療技術学部, 教授 (30286447)

Project Period (FY) 2017-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2019: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2018: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywords診療ガイドライン / 推奨グレード / 利益不利益バランス / 意思決定モデル / 多元的判断分析 / 階層評価法 / 医療経済学 / がん検診 / 政策決定
Outline of Final Research Achievements

When we make a recommendation for clinical practice guidelines (CPGs), the balance of benefits and harms should be always considered. To establish a standard method to make recommendations for CPGs, we investigated as follows: a literature review for adaptation of Multiple Criteria Decision Analysis (MCDA) in CPGs; comparison of the method to evaluate benefit and harms in CPG development; MCDA adaptation for guideline development of cervical cancer screening. To introduce MCDA for CPGs, the process to make recommendations has been clarified and can be reflected by various perspectives, including clinical practice, nursing, and public health. In the process of making recommendations for CPGs, MCDA is a useful method and it can be contributed to reducing evidence-practice gaps between CPGs and clinical settings.

Academic Significance and Societal Importance of the Research Achievements

診療ガイドライン作成には、推奨グレード決定プロセスの透明化・標準化が要である。同時に、利益不利益バランス、医療資源、患者価値観等の多元的評価が求められる。本研究では、子宮頸がん検診ガイドライン作成に諸外国の医療技術評価や政策決定に応用されているMultiple Criteria Decision Analysis(MCDA)を応用した。MCDAにより、患者や臨床医など異なる立場の意見を公平に反映した多元的評価が可能となった。診療ガイドライン作成において、MCDAは推奨グレード決定プロセスを透明化・標準化し、エビデンス・プラクティス・ギャップの解消に寄与する。

Report

(4 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Research-status Report
  • 2017 Research-status Report
  • Research Products

    (31 results)

All 2020 2019 2018 2017 Other

All Journal Article (12 results) (of which Int'l Joint Research: 2 results,  Peer Reviewed: 8 results,  Open Access: 7 results) Presentation (18 results) (of which Int'l Joint Research: 14 results,  Invited: 6 results) Remarks (1 results)

  • [Journal Article] The burden of gastric cancer2020

    • Author(s)
      Hamashima C
    • Journal Title

      Ann Transl Med

      Volume: - Issue: 12 Pages: 734-734

    • DOI

      10.21037/atm.2020.03.166

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Helicobacter p ylori eradication treatment for gastric carcinoma prevention in asymptomatic or dyspeptic adults: Systematic review and Bayesian meta-analysis of randomised controlled trials2019

    • Author(s)
      Terasawa Teruhiko、Hamashima Chisato、Kato Katsuaki、Miyashiro Isao、Yoshikawa Takaki、Takaku Reo、Nishida Hiroshi
    • Journal Title

      BMJ Open

      Volume: 9 Issue: 9 Pages: e026002-e026002

    • DOI

      10.1136/bmjopen-2018-026002

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Treatment of patients with early-stage colorectal cancer: ASCO resource-stratified guideline2019

    • Author(s)
      Costas-Chavarri A, Nandakumar G, Temin S, Lopes G, Cervantes A, Correa MC, Engineer R, Hamashima C, Ho GF, Huitzil FD, Moghani MM, Sharara AI, Stern MC, Teh C, Vazquez Manjarrez SE, Verjee A, Yantiss R, and Shah MA
    • Journal Title

      Journal of Global Oncology

      Volume: 2019 Issue: 5 Pages: 1

    • DOI

      10.1200/jgo.18.00214

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Early detection for colorectal cancer: ASCO resource-stratified guideline2019

    • Author(s)
      Lopes G, Stern MC, Temin S, Sharara AI, Cervantes A, Costas-Chavarri A, Engineer R, Hamashima C, Ho GF, Huitzil FD, Moghani MM, Nandakumar G, Shah MA, Teh C, Manjarrez SE, Verjee A, Yantiss R, and Correa MC
    • Journal Title

      Journal of Global Oncology

      Volume: 2019 Issue: 5 Pages: 1

    • DOI

      10.1200/jgo.18.00213

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Update version of the Japanese Guidelines for Gastric Cancer Screening2018

    • Author(s)
      Hamashima Chisato、Systematic Review Group and Guideline Development Group for Gastric Cancer Screening Guidelines
    • Journal Title

      Japanese Journal of Clinical Oncology

      Volume: 48 Issue: 7 Pages: 673-683

    • DOI

      10.1093/jjco/hyy077

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 有効性評価に基づく胃がん検診ガイドライン基礎となった臨床研究2018

    • Author(s)
      濱島ちさと
    • Journal Title

      胃と腸

      Volume: 53(8) Pages: 1163-1167

    • Related Report
      2018 Research-status Report
  • [Journal Article] Cancer screening guidelines and policy making: 15 years of experience in cancer screening guideline development in Japan2018

    • Author(s)
      Hamashima Chisato
    • Journal Title

      Japanese Journal of Clinical Oncology

      Volume: 48 Issue: 3 Pages: 278

    • DOI

      10.1093/jjco/hyx190

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Association between age factors and strategies for promoting participation in gastric and colorectal cancer screenings2018

    • Author(s)
      Hamashima Chisato、Sano Hiroshi
    • Journal Title

      BMC Cancer

      Volume: 18 Issue: 1 Pages: 345-345

    • DOI

      10.1186/s12885-018-4244-6

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] がん検診に関する最近の知見:2010年以降の研究とガイドライン2017

    • Author(s)
      濱島ちさと
    • Journal Title

      日本がん検診・診断学会誌

      Volume: 24(3) Pages: 270-281

    • Related Report
      2017 Research-status Report
  • [Journal Article] Does lack of resources impair access to breast and cervical cancer screening in Japan?2017

    • Author(s)
      Sano Hiroshi、Goto Rei、Hamashima Chisato
    • Journal Title

      PLOS ONE

      Volume: 12 Issue: 7 Pages: 99-99

    • DOI

      10.1371/journal.pone.0180819

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 対策型胃がん検診における胃内視鏡検査の導入と残された問題点2017

    • Author(s)
      濱島ちさと
    • Journal Title

      消化器内視鏡

      Volume: 29(7) Pages: 1152-1157

    • Related Report
      2017 Research-status Report
  • [Journal Article] 対策型検診のための胃内視鏡検診マニュアル2017

    • Author(s)
      濱島ちさと
    • Journal Title

      伊丹市医師会誌

      Volume: 173 Pages: 17-17

    • Related Report
      2017 Research-status Report
  • [Presentation] Gastric cancer screening program in Japan.2020

    • Author(s)
      Hamashima C
    • Organizer
      Gastric Cancer Summit 2020
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Systematic review of overdiagnosis and cost-effectiveness analysis in cervical cancer screening: How can overdiagnosis be included in cost-effectiveness analysis?2019

    • Author(s)
      Hamashima C
    • Organizer
      International Health Economics Association
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Cervical Cancer screening Program in Japan.2019

    • Author(s)
      Hamashima C
    • Organizer
      The 11th International Asian Conference on Cancer Screening
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] A systematic review of cost-effectiveness analysis in cervical cancer screening: How can overdiagnosis be included in cost-effectiveness analysis?2019

    • Author(s)
      Hamashima C
    • Organizer
      Preventing overdiagnosis Conference 2019
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Should we accept an intensive surveillance for patients with Li-fraumeni syndrome?2019

    • Author(s)
      Hamashima C
    • Organizer
      Preventing overdiagnosis Conference 2019
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Systematic review of overdiagnosis in cervical cancer screening: How should we define overdiagnosis in cervical cancer screening?2018

    • Author(s)
      Hamashima C
    • Organizer
      Preventing Overdiagnosis Conference 2018
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research
  • [Presentation] システマティックレビュー2018

    • Author(s)
      濱島ちさと
    • Organizer
      国際医薬経済・アウトカム研究学会(ISPOR)日本部会
    • Related Report
      2018 Research-status Report
  • [Presentation] Gastric cancer screening: Current issues and future perspective2018

    • Author(s)
      濱島ちさと
    • Organizer
      第90回日本胃癌学会総会
    • Related Report
      2017 Research-status Report
    • Invited
  • [Presentation] Quality assurance of evidence-based gastric cancer screening in Japanese communities2017

    • Author(s)
      Hamashima C
    • Organizer
      The Cancer and Primary Care Research International Network
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Oversupply of CT and MRI equipment, but undersupply of mammography equipment in Japan2017

    • Author(s)
      Hamashima C
    • Organizer
      International Society for Pharmacoeconomics and Outcomes Research 22nd Annual International Meeting
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Potential capacity of endoscopic screening for gastric cancer in Japan2017

    • Author(s)
      Hamashima C, Goto R
    • Organizer
      International Cancer Screening Network 2017
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Mortality reduction from gastric cancer by endoscopic screening: 6-years follow-up of a population-based cohort study2017

    • Author(s)
      Hamashima C, Shabana M, Osaki Y, Okada K
    • Organizer
      International Cancer Screening Network 2017
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Overdiagnosis on endoscopic screening for gastric cancer in Japan2017

    • Author(s)
      Hamashima C, Narisawa R
    • Organizer
      International Cancer Screening Network 2017
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Potential capacity of endoscopic screening for gastric cancer in Japan2017

    • Author(s)
      Hamashima C
    • Organizer
      12th World Congress of the International Health Economics Association
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] The policy of HPV Vaccine in Japan2017

    • Author(s)
      Hamashima C
    • Organizer
      HPV Vaccine and Cervical Cancer Prevention Control Forum
    • Related Report
      2017 Research-status Report
    • Invited
  • [Presentation] ROC analysis of prediction for gastric cancer development using serum pepsinogen and Helicobacter pylori antibody tests2017

    • Author(s)
      Hamashima C
    • Organizer
      2017 Global Evidence Summit
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Mortality reduction from gastric cancer by endoscopic screening based on a population-based cohort study2017

    • Author(s)
      Hamashima C
    • Organizer
      2017 Global Evidence Summit
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Screening Strategies for NCDs in Japan: New screening system for gastric cancer screening2017

    • Author(s)
      Hamashima C
    • Organizer
      2017 Global Health Forum in Taiwan
    • Related Report
      2017 Research-status Report
    • Invited
  • [Remarks] 科学的根拠に基づくがん検診推進のページ

    • URL

      http://canscreen.ncc.go.jp/

    • Related Report
      2017 Research-status Report

URL: 

Published: 2017-04-28   Modified: 2021-02-19  

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