A direct range visualization method by C-10 3-gamma Compton-PETfor C-ion therapy
| Project/Area Number |
17K09076
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Medical Physics and Radiological Technology
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| Research Institution | National Institutes for Quantum and Radiological Science and Technology |
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Principal Investigator |
Mohammadi Akram 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所 先進核医学基盤研究部, 主任研究員(任常) (10554735)
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| Project Period (FY) |
2017-04-01 – 2021-03-31
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| Project Status |
Completed (Fiscal Year 2020)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2019: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2018: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2017: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Keywords | 粒子線治療学 / Compton PET / triple gamma-ray imaging / visualization of C-10 / PET / Compton camera |
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| Outline of Final Research Achievements |
In heavy ion therapy, where the cancer treatment using heavy ions has significant advantages, verification of the ion rage inside the patient’s body is an important issue. In this study, we focused on detection of C-10 nuclide, which emits a positron and a single gamma ray at the same time, by combining the PET and Compton camera Methods. First the feasibility of proposed method was checked by performing Monte Carlo simulation and then we made a small-scale prototype of the device (whole-gamma imaging (WGI)) and conducted a demonstration experiment at the HIMAC secondary beam port.
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| Academic Significance and Societal Importance of the Research Achievements |
The major advantage of heavy ion therapy is a good dose localization and it is desirable to reduce range ambiguities in treatment planning for making full use of the major advantage. We developed a range verification system using C-10 beams to verify the ranges in patients directly.
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Report
(5 results)
Research Products
(8 results)
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[Journal Article] Influence of momentum acceptance on range monitoring of 11C and 15O ion beams using in-beam PET2020
Author(s)
Akram Mohammadi, Hideaki Tashima, Yuma Iwao, Sodai Takyu, Go Akamatsu, Han Gyu Kang, Fumihiko Nishikido, Eiji Yoshida, Andrew Chacon, Mitra Safavi-Naeini, Katia Parodi and Taiga Yamaya
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Journal Title
Physics in Medicine & Biology
Volume: 65
Issue: 12
Pages: 125006-125006
DOI
Related Report
Peer Reviewed / Int'l Joint Research
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