Innovative approach to health evaluation of non-infectious disease risk measurement by multivariate network meta-analysis
| Project/Area Number |
17K09213
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Hygiene and public health
|
|---|
| Research Institution | Teikyo University |
|---|
Principal Investigator |
Yamaoka Kazue 帝京大学, 大学院公衆衛生学研究科, 客員教授 (50091038)
|
|---|
| Project Period (FY) |
2017-04-01 – 2023-03-31
|
| Project Status |
Completed (Fiscal Year 2022)
|
| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2019: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2018: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2017: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
|
|---|
| Keywords | 非感染症疾患 / リスク / 多変量ネットワーク・メタアナリシス / 医療技術評価 / 糖尿病 / メタボリックシンドローム / アンブレラ・メタアナリシス / 非感染性疾患 / 多変量ネットワーク・メタ分析 / メタアナリシス |
|---|
| Outline of Final Research Achievements |
The increase in NCDs in recent years has been incredible. This study focused on diabetes, an important risk factor for NCDs, and conducted an integrated analysis of two life stages, middle and older age, using an umbrella meta-analysis of RCTs. Pooled odds ratios for lifestyle intervention (66 studies, 45878 participants) were 0.65 (0.53-0.80) and for metformin (8 studies, 5847 participants) was 0.71 (0.64-0.78). As for lifestyle, those were somewhat different by age groups, though the tendency was affected by the cut-off point of age. Further study is warranted.
|
| Academic Significance and Societal Importance of the Research Achievements |
学術的意義として、RCT研究を対象としたNCDsリスクに対する投薬・治療およびライフスタイル教育介入を、主要なリスクを総体として多変量ネットワーク・メタアナリシスにより捉え提示することがある。なかでもライフスタイル改善などの教育介入のコンプライアンスが低い原因の1つとして、効果の評価のエビデンスが明確ではないことがあり、総合した効果として明らかにされれば改善のための教育も含めた対策の意義がより明確になり、効果的戦略となりうる可能性が高まり、社会的意義がある。
|
Report
(7 results)
Research Products
(53 results)
-
-
-
-
-
-
-
-
-
-
[Journal Article] Living with lung cancer - Illness perceptions and quality of life in patients with non-small-cell lung cancer - a 3-month follow-up study.2020
Author(s)
Vollmann M, Matsuda A, Kroep JR, Kobayashi K, Kubota K, Inoue K, Yamaoka K, Putter H, Ramai R, Nortier HWR, Fischer MJ, Kaptein A.
-
Journal Title
Patient Related Outcome Measures
Volume: 11
Pages: 67-71
Related Report
-
[Journal Article] Breast cancer provider interval length in Fukushima, Japan, following the 2011 triple disaster: a long-term retrospective study.2020
Author(s)
Ozaki A, Nomura S, Leppold C, Tsubokura M, Sawano T, Tsukada M, Morita T, Tanimoto T, Saji S, Kato S, Yamaoka K, Nakata Y, Ohira H.
-
Journal Title
Clinical Breast Cancer
Volume: 20(2)
Issue: 2
Pages: 1526-8209
DOI
Related Report
Peer Reviewed / Open Access
-
-
[Journal Article] Validity and Reliability of the Japanese Version of the 10-Item Perceived Efficacy in Patient-Physician Interactions (PEPPI-10) Scale in Breast Cancer Outpatients2019
Author(s)
Matsuda A, Inoue K, Momiyama M, Kobayashi K, Kubota K, Ohkubo T, Fischer MJ, Kroep JR, Ramai SSRS, Kaptein AA, Yamaoka K.
-
Journal Title
The Tohoku Journal of Experimental Medicine
Volume: 249
Issue: 2
Pages: 121-126
DOI
NAID
ISSN
0040-8727, 1349-3329
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
[Presentation] Social support plays a critical role in enhancing mental health among HIV-infected patients in Hanoi, Vietnam2017
Author(s)
Matsumoto S, Yamaoka K, Takahashi K, Tanuma J, Mizushima D, Nguyen DT, Nguyen DT, Nguyen KV, Do CD, Oka S.
Organizer
Asia Pacific Conference on AIDS & CO-Infections
Related Report
Int'l Joint Research
-
-
