| Project/Area Number |
17K09224
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Hygiene and public health
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| Research Institution | Tezukayama Gakuin University (2020-2021)
Foundation for Biomedical Research and Innovation at Kobe (2017-2019) |
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Principal Investigator |
KUBO SACHIMI 帝塚山学院大学, 人間科学部, 准教授 (10782443)
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| Co-Investigator(Kenkyū-buntansha) |
岡村 智教 慶應義塾大学, 医学部(信濃町), 教授 (00324567)
斉藤 功 大分大学, 医学部, 教授 (90253781)
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| Project Period (FY) |
2017-04-01 – 2022-03-31
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| Project Status |
Completed (Fiscal Year 2021)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2020: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2019: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2018: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Keywords | フレイル / 高齢者 / 都市部住民 / 非都市部住民 / 疫学調査 / 生活習慣 / 食生活状況 / プレフレイル / コホート研究 / 神戸研究 / 東温スタディ / 地域比較 / 神戸トライアル / 高齢者保健 |
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| Outline of Final Research Achievements |
We compared the frailty risk factors in urban and non-urban areas and analyzed the factors for predicting frailty. The risk of prefrailty and frailty was associated with obesity, psychological stress, and physical activity. In comparison between urban and non-urban areas, the proportion of obese, no-exercise habit, and difficulty in walking for 1 km or more was high in non-urban areas. In urban women, the proportion of undernourished persons and who feel that muscle and fat have recently fallen was high compared with non-urban areas. However, there was no difference in the proportion of patients with sarcopenia. The frailty frequency in urban areas was 64.8% in males and 65.5% in females aged 70 years or older, including 90.9% in males aged 80 years or older and 76.9% in females.
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| Academic Significance and Societal Importance of the Research Achievements |
プレフレイル、フレイルのリスク要因として肥満や心理ストレス、身体活動量との関連が示唆された。都市部と非都市部では生活習慣が異なるため、肥満者や低栄養者の割合、運動習慣等に地域差が認められたが、サルコペニア該当者割合には差は認められなかった。今後フレイル発症者を効果的に抑制するためには、適切な地域診断を実施し、対象地域の特性に応じたアプローチを実施する必要があると考えられた。
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