| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2019: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2018: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2017: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Outline of Final Research Achievements |
Although human milk fortification (HMF) is the standard nutritional management for preterm infants, it currently does not prevent extrauterine growth restriction during NICU admission. We conducted a randomized controlled trial to compare the efficacy and safety of early HMF with those of conventional HMF (delayed HMF). Comparison between the two groups showed no difference in the number of days to establish enteral nutrition or to wean from parenteral nutrition, indicating that early HMF can be safely implemented without increasing feeding intolerance. On the other hand, there were no differences in outcomes such as anthropometric measurements at NICU discharge or developmental delay at the modified 18-month age point.
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