| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2019: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2018: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2017: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
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| Outline of Final Research Achievements |
Three-hundred seventy-two subjects were enrolled in the present study. Parental rearing and personality were evaluated, and methylation levels of the BDNF gene were quantified by the bisulfite-pyrosequencing method. The following results were found.
1. In 98 healthy Japanese, the subjects with higher neuroticism scores had higher levels of BDNF gene methylation compared with those with lower neuroticism scores. Meanwhile, other personality traits were not associated with BDNF gene methylation. 2. Positive correlation between the BDNF gene methylation levels and sociotropy scores was found. Sociotropy scores were positively correlated with maternal protection.
These findings were made public in the form of an article and in the scientific meetings. A article is in submission.
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