| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2020: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2019: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2018: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Outline of Final Research Achievements |
The first study aimed to develop a salivary biomarker for attention-deficit/hyperactivity disorder (ADHD) in children. Saliva levels of 27 cytokines were measured in samples collected from 19 children with significant ADHD symptoms and 17 without. A significant difference between groups was observed in the levels of several of the cytokines measured.
The second study aimed to develop a salivary biomarker to monitor stress in adolescents. Saliva levels of 27 cytokines were measured in samples collected from 31 health participants (mean age [SD] = 21.5 [0.8] years). The associations of cytokine levels with sleep, stress, and attention were examined. Stress was significantly associated with alterations of the Th1/Th2 balance in salivary cytokines.
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