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The new diagnostic method in detection of cutaneous sentinel lymph node by nuclear medicine method

Research Project

Project/Area Number 17K10429
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Radiation science
Research InstitutionHirosaki University

Principal Investigator

Miura Hiroyuki  弘前大学, 医学部附属病院, 講師 (10271826)

Co-Investigator(Kenkyū-buntansha) 金子 高英  順天堂大学, 医学部, 准教授 (20333718)
Project Period (FY) 2017-04-01 – 2021-03-31
Project Status Completed (Fiscal Year 2020)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2019: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2018: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords皮膚悪性腫瘍 / センチネルリンパ節 / 核医学 / 時間放射能曲線 / 画像診断 / 加算画像
Outline of Final Research Achievements

In detection of the sentinel lymph nodes (SLN) in patients with malignant skin neoplasms, the analyze of the time activity curve as a new diagnosis of SLNs and the create of the addition imaging were tried.
And the pattern analysis of the lymphatic drainage and lymph nodes, the existence of the necessity for the dynamic image, radiologists' contribution, the analyze of the time activity curve for every site, and analysis of in detection of recurrence and metastasis in follow up diagnostic modalities CT, MRI, FDG PET/CT)were summarized.

Academic Significance and Societal Importance of the Research Achievements

皮膚悪性腫瘍例におけるセンチネルリンパ節(SLV)の核医学的検出において、動態像および時間放射能曲線の解析によって診断能が向上するのを確認した。それにより従来に比して過不足のない生検が行うことが可能と考えられる。
SLNの核医学的検出施行例の経過観察画像を解析し、SLN転移の有無や、SLN転移陽性例での廓清時の転移の有無で、再発や転移の頻度に有意差があるのを確認し、診療方針決定の上での有用な情報が得られた。

Report

(5 results)
  • 2020 Annual Research Report   Final Research Report ( PDF )
  • 2019 Research-status Report
  • 2018 Research-status Report
  • 2017 Research-status Report
  • Research Products

    (9 results)

All 2020 2019 2018 2017 2016

All Journal Article (5 results) (of which Open Access: 4 results,  Peer Reviewed: 4 results) Presentation (4 results) (of which Invited: 1 results)

  • [Journal Article] Current status of radioligand therapy and positron-emission tomography with prostate-specific membrane antigen2020

    • Author(s)
      Inubushi Masayuki、Miura Hiroyuki、Kuji Ichiei、Ito Kimiteru、Minamimoto Ryogo
    • Journal Title

      Annals of Nuclear Medicine

      Volume: 34 Issue: 12 Pages: 879-883

    • DOI

      10.1007/s12149-020-01549-5

    • Related Report
      2020 Annual Research Report
    • Open Access
  • [Journal Article] Pyogenic granuloma-like Kaposi's sarcoma on the first toe2018

    • Author(s)
      Korekawa Ayumi、Kaneko Takahide、Nakano Hajime、Sawamura Daisuke
    • Journal Title

      The Journal of Dermatology

      Volume: 45 Issue: 7

    • DOI

      10.1111/1346-8138.14251

    • Related Report
      2018 Research-status Report
    • Peer Reviewed
  • [Journal Article] ANATOMICAL CLASSIFICATION OF BREAST SENTINEL LYMPH NODES USING COMPUTED TOMOGRAPHY LYMPHOGRAPHY2018

    • Author(s)
      Tamaki Fujita, Hiroyuki Miura, Hiroko Seino, Shuichi Ono, Takashi Nishi, Akimasa Nishimura, Kenichi Hakamada, Masahiko Aoki
    • Journal Title

      Anatomical Science International

      Volume: - Issue: 4 Pages: 1-8

    • DOI

      10.1007/s12565-018-0441-2

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Psoriasis Area and Severity Index is closely related to serum C-reactive protein level and neutrophil to lymphocyte ratio in Japanese patients2017

    • Author(s)
      Minakawa Satoko、Kaneko Takahide、Matsuzaki Yasushi、Yamada Masahiro、Kayaba Hiroyuki、Sawamura Daisuke
    • Journal Title

      The Journal of Dermatology

      Volume: 44 Issue: 10

    • DOI

      10.1111/1346-8138.13942

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Usefulness of ultrasonography in the diagnosis of ischaemic fasciitis.2016

    • Author(s)
      Kaneko T, Rokunohe D, Takiyoshi N, Minakawa S, Nakano H, Sawamura D
    • Journal Title

      Clin Exp Dermatol

      Volume: 41 Issue: 6 Pages: 502-505

    • DOI

      10.1111/ijd.12380

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] 皮膚悪性腫瘍例のセンチネルリンパ節の核医学的検出に関する検討 約16年間 やってみた -これまで、そして、これから?-2019

    • Author(s)
      三浦弘行
    • Organizer
      第62回北日本核医学談話会
    • Related Report
      2019 Research-status Report
    • Invited
  • [Presentation] センチネルリンパ節の核医学的検出施行例における皮膚悪性黒色腫の経過観察目的の画像検査2018

    • Author(s)
      三浦弘行、対馬史泰、掛端伸也、藤田大真、藤田環、辰尾小百合、辰尾宗一郎、柿﨑沙野、丸山翔、 小野修一、一瀬浩司、青木昌彦、金子高英、澤村大輔
    • Organizer
      第54回日本医学放射線学会秋季臨床大会
    • Related Report
      2018 Research-status Report
  • [Presentation] 体幹部皮膚悪性腫瘍症例のセンチネルリンパ節シンチグラフィの解析2017

    • Author(s)
      三浦弘行、対馬史泰、掛端伸也、藤田大真、藤田 環、田中円葵、辰尾宗一郎、辰尾小百合、柿崎沙野、小野修一、金子高英、澤村大輔、清野浩子
    • Organizer
      第57回日本核医学会学術総会
    • Related Report
      2017 Research-status Report
  • [Presentation] センチネルリンパ節の核医学的検出が行われた皮膚悪性黒色腫症例の再発・転移:経過観察の画像検査からの検討2017

    • Author(s)
      三浦弘行、対馬史泰、掛端伸也、藤田大真、藤田 環、田中円葵、辰尾小百合、辰尾宗一郎、柿﨑沙野、小野修一、青木昌彦、清野浩子、清野浩子
    • Organizer
      第19回SNNS研究会学術集会
    • Related Report
      2017 Research-status Report

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Published: 2017-04-28   Modified: 2022-01-27  

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